Recent advances in methamphetamine neurotoxicity mechanisms and its molecular pathophysiology

S Yu, L Zhu, Q Shen, X Bai, X Di - Behavioural neurology, 2015 - Wiley Online Library
Methamphetamine (METH) is a sympathomimetic amine that belongs to phenethylamine
and amphetamine class of psychoactive drugs, which are widely abused for their stimulant …

Methamphetamine addiction: involvement of CREB and neuroinflammatory signaling pathways

IN Krasnova, Z Justinova, JL Cadet - Psychopharmacology, 2016 - Springer
Rationale and objectives Addiction to psychostimulant methamphetamine (METH) remains a
major public health problem in the world. Animal models that use METH self-administration …

Current understanding of methamphetamine-associated dopaminergic neurodegeneration and psychotoxic behaviors

EJ Shin, DK Dang, TV Tran, HQ Tran, JH Jeong… - Archives of Pharmacal …, 2017 - Springer
Clinical and preclinical studies have indicated that chronic methamphetamine (MA) use is
associated with extensive neurodegeneration, psychosis, and cognitive impairment …

Role of mitochondria in methamphetamine-induced dopaminergic neurotoxicity: involvement in oxidative stress, neuroinflammation, and pro-apoptosis—a review

EJ Shin, HQ Tran, PT Nguyen, JH Jeong, SY Nah… - Neurochemical …, 2018 - Springer
Abstract Methamphetamine (MA), an amphetamine-type psychostimulant, is associated with
dopaminergic toxicity and has a high abuse potential. Numerous in vivo and in vitro studies …

Chronic methamphetamine self-administration disrupts cortical control of cognition

A Bernheim, RE See, CM Reichel - Neuroscience & Biobehavioral …, 2016 - Elsevier
Methamphetamine (meth) is one of the most abused substances worldwide. Chronic use
has been associated with repeated relapse episodes that may be exacerbated by cognitive …

Depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: relevance to motivation pathologies

G Bergamini, H Sigrist, B Ferger, N Singewald… - …, 2016 - Elsevier
Dopamine (DA) neurotransmission, particularly the ventral tegmental area-nucleus
accumbens (VTA-NAcc) projection, underlies reward and aversion processing, and deficient …

[HTML][HTML] Characterization of striatum-mediated behavior and neurochemistry in the DJ-1 knock-out rat model of Parkinson's disease

DM Giangrasso, TM Furlong, KA Keefe - Neurobiology of Disease, 2020 - Elsevier
The recently developed DJ-1 knockout (KO) rat models the DJ-1 (or PARK7) loss-of-function
mutation responsible for one form of early-onset familial Parkinson's disease (PD). Prior …

Positive and negative feedback learning and associated dopamine and serotonin transporter binding after methamphetamine

A Stolyarova, SJ O'Dell, JF Marshall… - Behavioural brain …, 2014 - Elsevier
Learning from mistakes and prospectively adjusting behavior in response to reward
feedback is an important facet of performance monitoring. Dopamine (DA) pathways play an …

The differential vulnerabilities of Per2 knockout mice to the addictive properties of methamphetamine and cocaine

LV Sayson, HJ Lee, DM Ortiz, M Kim… - Progress in Neuro …, 2023 - Elsevier
With the pervasive occurrence of substance abuse worldwide, unraveling the
neuropharmacology of drugs of abuse, such as psychostimulants, is undeniably essential …

Methamphetamine-induced neurotoxicity disrupts pharmacologically evoked dopamine transients in the dorsomedial and dorsolateral striatum

JD Robinson, CD Howard, ED Pastuzyn, DL Byers… - Neurotoxicity …, 2014 - Springer
Phasic dopamine (DA) signaling, during which burst firing by DA neurons generates short-
lived elevations in extracellular DA in terminal fields called DA transients, is implicated in …