The term “circadian rhythms” describes endogenous oscillations with ca. 24-h period
associated with the earth's daily rotation and light/dark cycle. Such rhythms reflect the …

The immune system is highly time-of-day dependent. Pioneering studies in the 1960s were
the first to identify immune responses to be under a circadian control. Only in the last …

Circadian clocks are endogenous oscillators that control 24-h physiological and behavioral
processes. The central circadian clock exerts control over myriad aspects of mammalian …

Trichuriasis and ascariasis are neglected tropical diseases caused by the gastrointestinal
dwelling nematodes Trichuris trichiura (a whipworm) and Ascaris lumbricoides (a …

Dendritic cells play a key role in processing and presenting antigens to naïve T cells to
prime adaptive immunity. Circadian rhythms are known to regulate many aspects of …

Migration of leukocytes from the skin to lymph nodes (LNs) via afferent lymphatic vessels
(LVs) is pivotal for adaptive immune responses,. Circadian rhythms have emerged as …

The adaptive immune response is under circadian control, yet, why adaptive immune
reactions continue to exhibit circadian changes over long periods of time is unknown. Using …

Laboratory mice have provided invaluable insight into mammalian immune systems. Yet the
immune phenotypes of mice bred and maintained in conventional laboratory conditions …

Food allergy affects more than 500 million people in the world, and its prevalence is
increasing at an alarming rate causing serious public health concerns; however, prevention …

Circadian variations of various aspects of the immune system have been described.
However, the circadian control of T cells has been relatively unexplored. Here, we …