The circadian system is responsible for internal functions and regulation of the organism
according to environmental cues (zeitgebers). Circadian rhythm dysregulation or …

24-h rhythms in physiology and behaviour are organized by a body-wide network of
endogenous circadian clocks. In mammals, a central pacemaker in the hypothalamic …

Circadian control of cell division is well established in diverse organisms. Recent single-cell
studies on mouse fibroblasts have shown that the circadian clock and cell cycle systems are …

Circadian rhythms control organismal physiology throughout the day. At the cellular level,
clock regulation is established by a self-sustained Bmal1-dependent transcriptional …

The circadian clock exerts an important role in systemic homeostasis as it acts a keeper of
time for the organism. The synchrony between the daily challenges imposed by the …

Most organisms evolved endogenous, so called circadian clocks as internal timekeeping
mechanisms allowing them to adapt to recurring changes in environmental demands …

Objective A network of endogenous circadian clocks adapts physiology and behavior to
recurring changes in environmental demands across the 24-hour day cycle. Circadian …

The mammalian circadian system is a hierarchically organized system, which controls a 24-
h periodicity in a wide variety of body and brain functions and physiological processes …

Chronotype has been mostly assessed with subjective scales. Objective assessment has
been undertaken with actigraphy, although problems may occur in classifying chronotype …

Host–microbiome interactions constitute key determinants of host physiology, while their
dysregulation is implicated in a wide range of human diseases. The microbiome undergoes …