Sexual development in Plasmodium parasites: knowing when it's time to commit
GA Josling, M Llinás - Nature Reviews Microbiology, 2015 - nature.com
Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …
Division and transmission: malaria parasite development in the mosquito
DS Guttery, M Zeeshan, DJP Ferguson… - Annual Review of …, 2022 - annualreviews.org
The malaria parasite life cycle alternates between two hosts: a vertebrate and the female
Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for …
Anopheles mosquito vector. Cell division, proliferation, and invasion are essential for …
UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein–DNA interactions
MA Hume, LA Barrera, SS Gisselbrecht… - Nucleic acids …, 2015 - academic.oup.com
Abstract The Universal PBM Resource for Oligonucleotide Binding Evaluation (UniPROBE)
serves as a convenient source of information on published data generated using universal …
serves as a convenient source of information on published data generated using universal …
Life cycle progression and sexual development of the apicomplexan parasite Cryptosporidium parvum
J Tandel, ED English, A Sateriale, JA Gullicksrud… - Nature …, 2019 - nature.com
The apicomplexan parasite Cryptosporidium is a leading global cause of severe diarrhoeal
disease and an important contributor to early childhood mortality. Currently, there are no …
disease and an important contributor to early childhood mortality. Currently, there are no …
A knockout screen of ApiAP2 genes reveals networks of interacting transcriptional regulators controlling the Plasmodium life cycle
K Modrzynska, C Pfander, L Chappell, L Yu, C Suarez… - Cell host & …, 2017 - cell.com
A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s)
was identified in malaria parasites. This family includes sequence-specific transcription …
was identified in malaria parasites. This family includes sequence-specific transcription …
ApiAP2 transcription factors in apicomplexan parasites
MD Jeninga, JE Quinn, M Petter - Pathogens, 2019 - mdpi.com
Apicomplexan parasites are protozoan organisms that are characterised by complex life
cycles and they include medically important species, such as the malaria parasite …
cycles and they include medically important species, such as the malaria parasite …
The modular circuitry of apicomplexan cell division plasticity
The close-knit group of apicomplexan parasites displays a wide variety of cell division
modes, which differ between parasites as well as between different life stages within a …
modes, which differ between parasites as well as between different life stages within a …
Genetic ablation of a female-specific apetala 2 transcription factor blocks oocyst shedding in Cryptosporidium parvum
The apicomplexan parasite Cryptosporidium is a leading global cause of diarrheal disease,
and the infection poses a particularly grave threat to young children and those with …
and the infection poses a particularly grave threat to young children and those with …
Opposing Transcriptional Mechanisms Regulate Toxoplasma Development
DP Hong, JB Radke, MW White - Msphere, 2017 - Am Soc Microbiol
The Toxoplasma biology that underlies human chronic infection is developmental
conversion of the acute tachyzoite stage into the latent bradyzoite stage. We investigated the …
conversion of the acute tachyzoite stage into the latent bradyzoite stage. We investigated the …
Cell cycle-regulated ApiAP2s and parasite development: the Toxoplasma paradigm
Highlights•AP2 factors are the major gene expression drivers of the T. gondii cell cycle.•AP2
factors can act as activators or repressors in complex with other players.•A distinct, shared …
factors can act as activators or repressors in complex with other players.•A distinct, shared …