Cell therapy, particularly mesenchymal stem/stromal (MSC) therapy, has been investigated
for a wide variety of disease indications, particularly those with inflammatory pathologies …

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Abstract Background Mesenchymal stromal cells (MSCs) have been extensively used in the
clinic due to their exquisite tissue repair capacity. However, they also hold promise in the …

Mesenchymal stromal cells (MSCs) are largely known for their immune-suppressive
capacity, hence, their common use in the control of unwanted inflammation. However, novel …

The Accum™ technology was initially designed to enhance the bioaccumulation of a given
molecule in target cells. It does so by triggering endosomal membrane damages allowing …

The extensive use of mesenchymal stromal cells (MSCs) over the last decade has
revolutionized modern medicine. From the delivery of pharmacological proteins to …

Immunosenescence occurs with progressive age. T cell aging is manifested by
immunodeficiency and inflammation. The main mechanisms are thymic involution …

Mesenchymal stromal cells (MSCs) have been modified via genetic or pharmacological
engineering into potent antigen-presenting cells-like capable of priming responding CD8 T …

Selective degradation of cellular proteins by the ubiquitin–proteasome system (UPS) is one
of the key regulatory mechanisms in eukaryotic cells. A growing body of evidence indicates …

Dendritic cells (DCs) play a protective role in the antitumor immunity of most cancers, which
can be divided into conventional dendritic cells (cDCs) and plasmacytoid dendritic cells …