The association between prenatal exposure to phthalates and cognition and neurobehavior of children-evidence from birth cohorts

Q Zhang, XZ Chen, X Huang, M Wang, J Wu - Neurotoxicology, 2019 - Elsevier
Background Phthalate have been detected widely in the environment; while several studies
have indicated that prenatal phthalate exposure has adverse effects on neurodevelopment …

Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways

H Mohammadi, S Ashari - Environmental Science and Pollution Research, 2021 - Springer
The wide use of phthalates, as phthalates are used in the manufacturing of not only plastics
but also many others goods, has become a main concern in the current century because of …

Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation

T Iizuka, P Yin, A Zuberi, S Kujawa… - Proceedings of the …, 2022 - National Acad Sciences
Uterine leiomyoma is the most common tumor in women and causes severe morbidity in 15
to 30% of reproductive-age women. Epidemiological studies consistently indicate a …

Lycopene preventing DEHP-induced renal cell damage is targeted by aryl hydrocarbon receptor

MZ Li, Y Zhao, HR Wang, M Talukder… - Journal of agricultural …, 2021 - ACS Publications
Di (2-ethylhexyl) phthalate (DEHP) is an environmentally persistent and bioaccumulative
plasticizer. Accumulation of DEHP in the body can eventually cause kidney damage. As a …

Di-(2-ethylhexyl) phthalate induced developmental abnormalities of the ovary in quail (Coturnix japonica) via disruption of the hypothalamic-pituitary-ovarian axis

XN Li, HX Li, TN Yang, XW Li, YQ Huang… - Science of The Total …, 2020 - Elsevier
An increasing number of epidemiologic studies show that women have a special exposure
profile to phthalates, and the exposures have attracted attention regarding their potential …

[HTML][HTML] Exposure to Di-(2-Ethylhexyl) phthalate drives ovarian dysfunction by inducing granulosa cell pyroptosis via the SLC39A5/NF-κB/NLRP3 axis

J Sun, L Gan, S Lv, T Wang, C Dai, J Sun - … and Environmental Safety, 2023 - Elsevier
Endocrine-disrupting chemicals (EDCs) have been reported to affect populations by
disrupting the human endocrine system. Di-(2-ethylhexyl) phthalate (DEHP) is an EDC that …

Exposure to di (2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive …

C Chiang, LR Lewis, G Borkowski, JA Flaws - Toxicology and applied …, 2020 - Elsevier
Abstract Di (2-ethylhexyl) phthalate (DEHP) is a phthalate commonly used for its plasticizing
capabilities. Because of the wide production and use of DEHP, humans are exposed to …

Probabilistic assessment of risks of diethylhexyl phthalate (DEHP) in surface waters of China on reproduction of fish

N Liu, Y Wang, Q Yang, Y Lv, X Jin, JP Giesy… - Environmental …, 2016 - Elsevier
Diethylhexyl phthalate (DEHP) is considered to be an endocrine disruptor, which unlike
other chemicals that have either non-specific (eg, narcotics) or more generalized reactive …

[HTML][HTML] Phthalate metabolites in urine and follicular fluid in relation to menstrual cycle characteristics in women seeking fertility assistance

J Li, T Deng, W Rao, H Liao, Y Wang, N Guo… - Environment …, 2024 - Elsevier
Background Phthalates have been shown to disrupt the estrous cycle in animal studies.
However, epidemiological research investigating their associations with menstrual cycle …

The action of di-(2-ethylhexyl) phthalate (DEHP) in mouse cerebral cells involves an impairment in aryl hydrocarbon receptor (AhR) signaling

AK Wójtowicz, AM Sitarz-Głownia, M Szczęsna… - Neurotoxicity …, 2019 - Springer
Abstract Di-(2-ethylhexyl) phthalate (DEHP) is used as a plasticizer in various plastic
compounds, such as polyvinyl chloride (PVC), and products including baby toys, packaging …