Neural tube closure has been studied for many decades, across a range of vertebrates, as a
paradigm of embryonic morphogenesis. Neurulation is of particular interest in view of the …

This report calls on the nation—its leaders, its mental health research and service provision
agencies, its schools, its primary care medical systems, its community-based organizations …

Folate receptors (FRα, FRβ and FRγ) are cysteine-rich cell-surface glycoproteins that bind
folate with high affinity to mediate cellular uptake of folate. Although expressed at very low …

Preventing Mental, Emotional, and Behavioral Disorders Among Young People: Progress and
Possibilities | The National Academies Press Skip to main content Navigate to Help Ordering …

The ABA pain guidelines were developed 14 years ago and have not been revised despite
evolution in the practice of burn care. A sub-committee of the American Burn Association's …

Craniorachischisis is a rare but severe birth defect that results in a completely open neural
tube. Mouse mutants in planar cell polarity (PCP) signalling components have deficits in the …

Physical forces drive the movement of tissues within the early embryo. Classical and modern
approaches have been used to infer and, in rare cases, measure mechanical properties and …

Wnt signaling regulates cell proliferation and cell differentiation as well as migration and
polarity during development. However, it is still unclear how the Wnt ligand distribution is …

The closure of an open anatomical structure by the directed growth and fusion of two tissue
masses is a recurrent theme in mammalian embryology, and this process plays an integral …

Neural tube defects (NTDs) are very frequent congenital abnormalities in humans. Recently,
we have documented independent association of Vangl1 and Vangl2 gene mutations with …