The ongoing exponential rise in recording capacity calls for new approaches for analysing
and interpreting neural data. Effective dimensionality has emerged as an important property …

Sensory areas are spontaneously active in the absence of sensory stimuli. This
spontaneous activity has long been studied; however, its functional role remains largely …

Recent studies in mice have shown that orofacial behaviors drive a large fraction of neural
activity across the brain. To understand the nature and function of these signals, we need …

Neurophysiology has long progressed through exploratory experiments and chance
discoveries. Anecdotes abound of researchers listening to spikes in real time and noticing …

The cerebellar cortex has a key role in generating predictive sensorimotor associations. To
do so, the granule cell layer is thought to establish unique sensorimotor representations for …

The cerebellum is thought to help detect and correct errors between intended and executed
commands, and is critical for social behaviours, cognition and emotion,,–. Computations for …

The cerebellar cortex is an important system for relating neural circuits and learning. Its
promise reflects the longstanding idea that it contains simple, repeated circuit modules with …

Due to the size and opacity of vertebrate brains, it has until now been impossible to
simultaneously record neuronal activity at cellular resolution across the entire adult brain. As …

An influential framework within systems neuroscience posits that neural computations can
be understood in terms of low-dimensional dynamics in recurrent circuits. A number of …

While neural plasticity has long been studied as the basis of learning, the growth of large-
scale neural recording techniques provides a unique opportunity to study how learning …