Update on the diagnosis of tuberculosis
I Kontsevaya, AM Cabibbe, DM Cirillo… - Clinical Microbiology …, 2023 - Elsevier
Background Tuberculosis remains a global public health threat, and the development of
rapid and precise diagnostic tools is the key to enabling the early start of treatment …
rapid and precise diagnostic tools is the key to enabling the early start of treatment …
Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a 2023 TBnet/RESIST-TB consensus statement
J Domínguez, MJ Boeree, E Cambau… - The Lancet Infectious …, 2023 - thelancet.com
Drug-resistant tuberculosis is a substantial health-care concern worldwide. Despite culture-
based methods being considered the gold standard for drug susceptibility testing, molecular …
based methods being considered the gold standard for drug susceptibility testing, molecular …
A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics
CRyPTIC Consortium - PLoS biology, 2022 - journals.plos.org
The Comprehensive Resistance Prediction for Tuberculosis: an International Consortium
(CRyPTIC) presents here a data compendium of 12,289 Mycobacterium tuberculosis global …
(CRyPTIC) presents here a data compendium of 12,289 Mycobacterium tuberculosis global …
The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot
Multidrug-resistant tuberculosis (MDR-TB) is among the most frequent causes of death due
to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical …
to antimicrobial resistance. Although only 3% of global TB cases are MDR, geographical …
Tuberculosis treatment failure associated with evolution of antibiotic resilience
The widespread use of antibiotics has placed bacterial pathogens under intense pressure to
evolve new survival mechanisms. Genomic analysis of 51,229 Mycobacterium tuberculosis …
evolve new survival mechanisms. Genomic analysis of 51,229 Mycobacterium tuberculosis …
Drug-resistant tuberculosis: a persistent global health concern
Drug-resistant tuberculosis (TB) is estimated to cause 13% of all antimicrobial resistance-
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …
attributable deaths worldwide and is driven by both ongoing resistance acquisition and …
A convolutional neural network highlights mutations relevant to antimicrobial resistance in Mycobacterium tuberculosis
AG Green, CH Yoon, ML Chen, Y Ektefaie… - Nature …, 2022 - nature.com
Long diagnostic wait times hinder international efforts to address antibiotic resistance in M.
tuberculosis. Pathogen whole genome sequencing, coupled with statistical and machine …
tuberculosis. Pathogen whole genome sequencing, coupled with statistical and machine …
Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing of M. tuberculosis
CRyPTIC Consortium - European Respiratory Journal, 2022 - Eur Respiratory Soc
Drug susceptibility testing of M. tuberculosis is rooted in a binary susceptible/resistant
paradigm. While there are considerable advantages in measuring the minimum inhibitory …
paradigm. While there are considerable advantages in measuring the minimum inhibitory …
[PDF][PDF] Optimized broth microdilution plate methodology for drug susceptibility testing of Mycobacterium tuberculosis complex
World Health Organization - 2022 - apps.who.int
Under the terms of this licence, you may copy, redistribute and adapt the work for non-
commercial purposes, provided the work is appropriately cited, as indicated below. In any …
commercial purposes, provided the work is appropriately cited, as indicated below. In any …
Advancing pathogen genomics in resource-limited settings
PM Pronyk, R de Alwis, R Rockett, K Basile… - Cell Genomics, 2023 - cell.com
Genomic sequencing has emerged as a powerful tool to enhance early pathogen detection
and characterization with implications for public health and clinical decision making …
and characterization with implications for public health and clinical decision making …