Major coagulation disorders and parameters in COVID-19 patients

A Teimury, MT Khameneh, EM Khaledi - European journal of medical …, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), with a high prevalence rate, has rapidly
infected millions of people around the world. Since viral infections can disrupt the …

Tissue factor in COVID-19-associated coagulopathy

S Subramaniam, H Kothari, M Bosmann - Thrombosis Research, 2022 - Elsevier
Evidence of micro-and macro-thrombi in the arteries and veins of critically ill COVID-19
patients and in autopsies highlight the occurrence of COVID-19-associated coagulopathy …

Use of nafamostat mesilate for anticoagulation during extracorporeal membrane oxygenation: A systematic review

F Sanfilippo, JM Currò, L La Via, V Dezio… - Artificial …, 2022 - Wiley Online Library
Background Extracorporeal membrane oxygenation (ECMO) represents an advanced option
for supporting refractory respiratory and/or cardiac failure. Systemic anticoagulation with …

SARS-CoV-2 proteins and anti-COVID-19 drugs induce lytic reactivation of an oncogenic virus

J Chen, L Dai, L Barrett, J James… - Communications …, 2021 - nature.com
An outbreak of the novel coronavirus SARS-CoV-2, the causative agent of Coronavirus
Disease-2019 (COVID-19), a respiratory disease, has infected almost one hundred million …

Evaluation of various blood biomarkers associated with the outcomes of patients with COVID‑19 treated in intensive care units

S Genc… - Experimental and …, 2024 - spandidos-publications.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting
coronavirus disease 2019 (COVID-19) represented a global public health crisis and the …

COVID-19: a novel holistic systems biology approach to predict its molecular mechanisms (in vitro) and repurpose drugs

M Sameni, SA Mirmotalebisohi, S Dadashkhan… - DARU Journal of …, 2023 - Springer
Purpose COVID-19 strangely kills some youth with no history of physical weakness, and in
addition to the lungs, it may even directly harm other organs. Its complex mechanism has led …

Advocacy of targeting protease‐activated receptors in severe coronavirus disease 2019

S Subramaniam, W Ruf… - British journal of …, 2022 - Wiley Online Library
Identifying drug targets mitigating vascular dysfunction, thrombo‐inflammation and
thromboembolic complications in COVID‐19 is essential. COVID‐19 coagulopathy differs …

Unfractionated heparin versus nafamostat mesylate for anticoagulation during continuous kidney replacement therapy: an observational study

S Kameda, T Fujii, J Ikeda, A Kageyama, T Takagi… - BMC nephrology, 2023 - Springer
Background Unfractionated heparin sodium and nafamostat mesylate have long been used
as anticoagulants in continuous kidney replacement therapy (CKRT) where citrate is …

Coagulation abnormalities and clinical complications in children with SARS-CoV-2: a systematic review of 48,322 patients

CG McDaniel, SJ Commander, I DeLaura… - Journal of pediatric …, 2022 - journals.lww.com
Given the limited information on the coagulation abnormalities of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) in pediatric patients, we designed a systematic …

Complement system component dysregulation is a distinctive feature of COVID-19 disease: A prospective and comparative analysis of patients admitted to the …

N Gauchel, M Rieder, K Krauel, I Goller… - Journal of Thrombosis …, 2022 - Springer
The complement system (CS) plays a pivotal role in Coronavirus disease 2019 (COVID-19)
pathophysiology. The objective of this study was to provide a comparative, prospective data …