Therapeutic resistance and metastatic progression are responsible for the majority of cancer
mortalities. In particular, the development of resistance is a significant barrier to the efficacy …

Transforming growth factor-beta (TGF-β) plays multiple homeostatic roles in the regulation of
inflammation, proliferation, differentiation and would healing of various tissues. Many studies …

Epithelial to mesenchymal transition (EMT) contributes to tumor progression, cancer cell
invasion, and therapy resistance. EMT is regulated by transcription factors such as the …

With 1.67 million new cases and 522,000 deaths in the year 2012, breast cancer is the most
common type of diagnosed malignancy and the second leading cause of cancer death in …

MicroRNA are non-coding small RNAs that bind to their target mRNA and cause mRNA
degradation or translation inhibition. MiRNA dysregulation is linked to a variety of human …

Extracellular-regulated kinases and p38 mitogen-activated protein kinases are activated in
innate (and adaptive) immunity and signal via different routes to alter the stability and …

Classification of ovarian cancer by morphologic features has a limited effect on serous
ovarian cancer (SOC) treatment and prognosis. Here, we proposed a new system for SOC …

Background EphA2 is a crucial oncogene in gastric cancer (GC) development and
metastasis, this study aims to identify microRNAs that target it and serve as key regulators of …

Acute myeloid leukaemia (AML) is characterized by uncontrolled proliferation of myeloid
progenitor cells and impaired maturation, leading to immature cell accumulation in the bone …

Background Recently, it has been reported that miRNA is involved in pterygium, however
the exact underlying mechanism in pterygium is unrevealed and require further …