As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5-
1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …

Ischemia/reperfusion injury (IRI) permeates a variety of diseases and is a ubiquitous
concern in every transplantation proceeding, from whole organs to modest grafts. Given its …

With an improved median survival of 6.2 years, lung transplantation has become an
increasingly acceptable treatment option for end-stage lung disease. Besides survival …

Advances in maintenance immunosuppression over the past three decades have improved
solid organ transplantation outcomes dramatically. Uninterrupted access to …

Oxidative stress is intensely involved in enhancing the severity of various chronic respiratory
diseases (CRDs) including asthma, chronic obstructive pulmonary disease (COPD) …

Background Lung transplantation is the final treatment option in the end stage of certain lung
diseases, once all possible conservative treatments have been exhausted. Depending on …

Purpose Lung transplant recipients often develop acute kidney injury (AKI) evolving into
chronic kidney disease (CKD). The immunosuppressant tacrolimus might be associated with …

Despite induction immunosuppression and the use of aggressive maintenance
immunosuppressive regimens, acute allograft rejection following lung transplantation is still …

Background. Lung transplantation is the only therapeutic option in end-stage lung diseases;
however, survival after transplantation is limited by acute and chronic rejection or infectious …

Long‐term survival after lung transplantation is limited by chronic allograft dysfunction. The
aim of this study was to investigate the effect of locally augmented immunosuppression with …