Alzheimer disease (AD) is the most common type of dementia in individuals over 65 years of
age. The neuropathological hallmarks of the condition are Tau neurofibrillary tangles and …

Animal models for anxiety, depressive-like and cognitive diseases or aging often involve
testing of subjects in behavioral test batteries. The large number of test variables with …

In laboratory rats, one of the most used paradigms to assess habituation to novelty is the
open-field test. Environmental enrichment has proved to be a reliable way to enhance open …

Highlights•Temperament in humans can be studied as individual differences in animal
models.•The hippocampus integrates the brain's response to stress, fear and drugs of …

The forced swim test (FST) is widely used to evaluate the antidepressant-like activity of
compounds and is sensitive to stimuli that cause depression-like behaviors in rodents. The …

Endometriosis is a disorder in which endometrial tissue is found outside the uterus causing
pain, infertility and stress. Finding effective, non-hormonal and long-term treatments for …

It has been described that environmental enrichment (EE) exerts beneficial effects on
cognitive and emotional performances, dendritic branching, synaptic density, neurogenesis …

Individual differences in coping with stress may determine either a vulnerable or resilient
phenotype. Therefore, it is important to better understand the biology underlying the …

The study of individual differences in the forced swimming test (FST) in rats allows the
identification of either susceptibility or resilience factors in the development of depression …

To investigate the effects of the Lycium barbarum L. polysaccharides (LBP) on anxiety,
depression and learning behaviors in ovariectomized female rats using the open field …