A biochemical assessment of apoptosis-inducing impact of Salinomycin in combination with ciprofloxacin on human leukemia KG1–a stem-like cells in the presence …

M Alhajamee, M Khalaj-Kondori, E Babaei… - Molecular Biology …, 2024 - Springer
Abstract Background Acute Myeloid Leukemia (AML) is a fast-developing invading cancer
that impacts the blood and bone marrow, marked by the rapid proliferation of abnormal white …

DNA binding, and apoptosis-inducing activities of a β-ionone-derived ester in human myeloid leukemia cells: multispectral and molecular dynamic simulation …

K Jahanbakhsh, R Ansari-Ahl, B Mashhadi, M Zare… - Scientific Reports, 2024 - nature.com
Abstract β-Ionone is the end-ring counterpart of β-carotenoids, which are widely found in
fruits and vegetables. Recent studies have illustrated the antimetastatic, anti-proliferative …

Design and synthesis of menthol and thymol derived ciprofloxacin: Influence of structural modifications on the antibacterial activity and anticancer properties

T Szostek, D Szulczyk, J Szymańska-Majchrzak… - International Journal of …, 2022 - mdpi.com
Sixteen new Ciprofloxacin derivatives were designed and successfully synthesized. In an in
silico experiment, lipophilicity was established for obtained compounds. All compounds …

A novel LL-37@ NH2@ Fe3O4 inhibits the proliferation of the leukemia K562 cells: in-vitro study

A Habibi, A Davari, K Isazadeh - Scientific Reports, 2024 - nature.com
LL-37 can inhibit the growth of K562 cancer cells when it is conjugated with iron oxide
nanoparticles. In this study, Fe3O4 nanoparticles were synthesized using the co …

Taify Pomegranate Juice Extract Abrogates Testicular Dysfunction Induced by Acrylamide: Role of Inflammatory, Antioxidants, and Oxidative Stress Biomarkers

MM Soliman, SM Sayed, GBA Youssef, S Athobaiti… - Andrologia, 2023 - Wiley Online Library
High altitude (HA) poses various dangers to living organisms, the most serious of which are
oxidative stress and its accompanying metabolic problems, as well as hypoxia and its …

[HTML][HTML] Dihydromyricetin Nanoparticles Alleviate Lipopolysaccharide-Induced Acute Kidney Injury by Decreasing Inflammation and Cell Apoptosis via the TLR4/NF …

H Yin, Q Yan, Y Li, H Tang - Journal of Functional Biomaterials, 2024 - mdpi.com
Acute kidney injury (AKI) is the most severe and fatal complication of sepsis resulting from
infectious trauma. Currently, effective treatment options are still lacking. Dihydromyricetin is …

[HTML][HTML] Regulation of survivin and caspase/Bcl-2/Cyto-C signaling by TDB-6 induces apoptosis of colorectal carcinoma LoVo cells

X Shi, P Wang, Y Zhu, L Li, T Yang, J Sun… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background Colorectal carcinoma (CRC) treatment remains severe. Survivin is aberrantly
overexpressed in CRC tissues and might be a potential target for CRC treatment. TDB-6 is a …

Evidence for Hesperidin as an Effective Factor in Initiating the Intrinsic Pathway of Apoptosis in KG1a Leukemia Cells

T Novinbahador, M Araj-Khodaei… - International Journal of …, 2023 - journals.sagepub.com
Acute myeloid leukemia (AML) is the most common subtype of leukemia, accounting for 62%
of all leukemia fatalities. As a polyphenol glycoside, hesperidin triggers the apoptotic …

An Active Compound from the Pyrazine Family Induces Apoptosis by Targeting the Bax/Bcl2 and Survivin Expression in Chronic Myeloid Leukemia K562 Cells

S Rostampour, F Eslami, E Babaei… - Anti-Cancer Agents …, 2024 - ingentaconnect.com
Background: It has been established that pyrazine derivatives, which have widespread
bioactivities, can effectively treat cancer. Objectives: In this study, we investigated the effects …

An immune-related signature predicted survival in patients with kidney papillary cell carcinoma

J Shen, R Wang, Y Chen, Z Fang, J Tang, J Yao… - Frontiers in …, 2021 - frontiersin.org
Immune-related genes are important factors in tumor progression. The main aim of this study
was to identify the immune-related genes in kidney papillary cell carcinoma (pRCC) …