Polymyalgia rheumatica

MA González-Gay, EL Matteson, S Castañeda - The Lancet, 2017 - thelancet.com
Polymyalgia rheumatica is an inflammatory disease that affects the shoulder, the pelvic
girdles, and the neck, usually in individuals older than 50 years. Increases in acute phase …

Giant-cell arteritis and polymyalgia rheumatica

CM Weyand, JJ Goronzy - New England Journal of Medicine, 2014 - Mass Medical Soc
Key Clinical Points Giant-Cell Arteritis and Polymyalgia Rheumatica The immune-mediated
diseases giant-cell arteritis and polymyalgia rheumatica occur in patients 50 years of age or …

Clinical features of polymyalgia rheumatica and giant cell arteritis

C Salvarani, N Pipitone, A Versari… - Nature Reviews …, 2012 - nature.com
Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are inflammatory diseases that
typically affect white individuals> 50 years. Women are affected∼ 2–3 times more often than …

Cytokine assays: an assessment of the preparation and treatment of blood and tissue samples

GCE Keustermans, SBE Hoeks, JM Meerding… - Methods, 2013 - Elsevier
Cytokines are key components of the innate and adaptive immune system. As pivotal
players in the progression or regression of a pathological process, these molecules provide …

Polymyalgia rheumatica

TA Kermani, KJ Warrington - The Lancet, 2013 - thelancet.com
Polymyalgia rheumatica is a chronic, inflammatory disorder of unknown cause that affects
people over age 50 years. Classic symptoms include pain and long-term morning stiffness of …

[HTML][HTML] Efficacy and Safety of Tofacitinib in Patients with Polymyalgia Rheumatica (EAST PMR): An open-label randomized controlled trial

X Ma, F Yang, J Wu, B Xu, M Jiang, Y Sun, C Sun… - PLoS …, 2023 - journals.plos.org
Background Polymyalgia rheumatica (PMR) is a common inflammatory disease in elderly
persons whose mechanism of pathogenesis has not been elucidated. Glucocorticoids are …

The immunopathology of giant cell arteritis: diagnostic and therapeutic implications

CM Weyand, YJ Liao, JJ Goronzy - Journal of Neuro …, 2012 - journals.lww.com
Giant cell arteritis (GCA) is an important cause of preventable blindness, most commonly
due to anterior ischemic optic neuropathy. Ischemic tissue injury is the end result of a …

Immune system activation in polymyalgia rheumatica: which balance between autoinflammation and autoimmunity? A systematic review

E Hysa, E Gotelli, S Sammori, MA Cimmino… - Autoimmunity …, 2022 - Elsevier
Background and aim Polymyalgia rheumatica (PMR) is an inflammatory rheumatic disease
that is common in elderly people. Its classification in the spectrum of autoinflammatory and …

[HTML][HTML] Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of B-Catenin

K Jähn, N Lara-Castillo, L Brotto, CL Mo… - European cells & …, 2012 - ncbi.nlm.nih.gov
It is a widely held belief that the sole effect of muscle on bone is through mechanical loading.
However, as the two tissues are intimately associated, we hypothesized that muscle …

The pathophysiology of polymyalgia rheumatica, small pieces of a big puzzle

GC Alegria, S Boukhlal, D Cornec… - Autoimmunity …, 2020 - Elsevier
Polymyalgia rheumatica (PMR) is a frequent rheumatic condition among people over 50
years of age. Despite its frequent association with giant cell arteritis (GCA), PMR can be …