[HTML][HTML] Cannabidiol as a potential treatment for anxiety disorders

EM Blessing, MM Steenkamp, J Manzanares… - …, 2015 - Elsevier
Cannabidiol (CBD), a Cannabis sativa constituent, is a pharmacologically broad-spectrum
drug that in recent years has drawn increasing interest as a treatment for a range of …

[HTML][HTML] Review of the neurological benefits of phytocannabinoids

J Maroon, J Bost - Surgical neurology international, 2018 - ncbi.nlm.nih.gov
Background: Numerous physical, psychological, and emotional benefits have been
attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopoeia …

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

AC Campos, FA Moreira, FV Gomes… - … of the Royal …, 2012 - royalsocietypublishing.org
Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It
lacks the psychotomimetic and other psychotropic effects that the main plant compound Δ 9 …

[HTML][HTML] Early phase in the development of cannabidiol as a treatment for addiction: opioid relapse takes initial center stage

YL Hurd, M Yoon, AF Manini, S Hernandez, R Olmedo… - …, 2015 - Elsevier
Multiple cannabinoids derived from the marijuana plant have potential therapeutic benefits
but most have not been well investigated, despite the widespread legalization of medical …

Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety‐related and substance abuse disorders

JLC Lee, LJ Bertoglio, FS Guimarães… - British journal of …, 2017 - Wiley Online Library
Learning to associate cues or contexts with potential threats or rewards is adaptive and
enhances survival. Both aversive and appetitive memories are therefore powerful drivers of …

Antidepressant-like and anxiolytic-like effects of cannabidiol: a chemical compound of Cannabis sativa

AR de Mello Schier… - CNS & Neurological …, 2014 - ingentaconnect.com
Anxiety and depression are pathologies that affect human beings in many aspects of life,
including social life, productivity and health. Cannabidiol (CBD) is a constituent non …

Cannabidiol, a Cannabis sativa constituent, as an anxiolytic drug

ARM Schier, NPO Ribeiro, ACO Silva… - Brazilian Journal of …, 2012 - SciELO Brasil
OBJECTIVES: To review and describe studies of the non-psychotomimetic constituent of
Cannabis sativa, cannabidiol (CBD), as an anxiolytic drug and discuss its possible …

Cannabidiol reduces ethanol consumption, motivation and relapse in mice

A Viudez‐Martínez, MS García‐Gutiérrez… - Addiction …, 2018 - Wiley Online Library
This study evaluated the effects of cannabidiol (CBD) on ethanol reinforcement, motivation
and relapse in C57BL/6 J mice. The effects of CBD (60 mg/kg, ip) on blood ethanol …

Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial …

RB Malvestio, P Medeiros, SE Negrini-Ferrari… - Brain Research …, 2021 - Elsevier
The prelimbic division (PrL) of the medial prefrontal cortex (mPFC) is a cerebral division that
is putatively implicated in the chronic pain and depression. We investigated the activity of …

CB1 receptor signalling mediates cannabidiol-induced panicolytic-like effects and defensive antinociception impairment in mice threatened by Bothrops jararaca …

BM de Paula Rodrigues… - Journal of …, 2022 - journals.sagepub.com
Background: Cannabis sativa-derived substances such as cannabidiol (CBD) have attracted
increasing clinical interest and consist in a new perspective for treating some neurological …