Near‐infrared‐II molecular dyes for cancer imaging and surgery

S Zhu, R Tian, AL Antaris, X Chen, H Dai - Advanced Materials, 2019 - Wiley Online Library
Fluorescence bioimaging affords a vital tool for both researchers and surgeons to
molecularly target a variety of biological tissues and processes. This review focuses on …

Microneedles-based transdermal drug delivery systems: a review

Y Hao, W Li, XL Zhou, F Yang… - Journal of biomedical …, 2017 - ingentaconnect.com
A microneedle (MN) is a micron-sized needle with a height of 10–2000 μm and a width of 10–
50 μm, which can penetrate through the epidermis layer to dermal tissue directly without …

Biodegradable manganese-doped calcium phosphate nanotheranostics for traceable cascade reaction-enhanced anti-tumor therapy

LH Fu, YR Hu, C Qi, T He, S Jiang, C Jiang, J He, J Qu… - Acs Nano, 2019 - ACS Publications
Glucose oxidase (GOx) has been recognized as a “star” enzyme catalyst involved in cancer
treatment in the past few years. Herein, GOx is mineralized with manganese-doped calcium …

Biomineralized bacterial outer membrane vesicles potentiate safe and efficient tumor microenvironment reprogramming for anticancer therapy

S Qing, C Lyu, L Zhu, C Pan, S Wang, F Li… - Advanced …, 2020 - Wiley Online Library
The highly immunosuppressive tumor microenvironment (TME) in solid tumors often
dampens the efficacy of immunotherapy. In this study, bacterial outer membrane vesicles …

A pH‐triggered self‐unpacking capsule containing zwitterionic hydrogel‐coated MOF nanoparticles for efficient oral exendin‐4 delivery

Y Zhou, Z Chen, D Zhao, D Li, C He… - Advanced …, 2021 - Wiley Online Library
Oral peptide or protein delivery is considered a revolutionary alternative to daily
subcutaneous injection; however, major challenges remain in terms of impediments of the …

Calcium-based biomaterials for diagnosis, treatment, and theranostics

C Qi, J Lin, LH Fu, P Huang - Chemical Society Reviews, 2018 - pubs.rsc.org
Calcium-based (CaXs) biomaterials including calcium phosphates, calcium carbonates,
calcium silicate and calcium fluoride have been widely utilized in the biomedical field owing …

Biomineralized Polydopamine nanoparticle-based Sodium Alginate Hydrogels for delivery of Anti-serine/Threonine protein kinase B-Rapidly accelerated …

J Lu, J Song, P Zhang, Y Huang, X Lu, H Dai, J Xi - ACS nano, 2023 - ACS Publications
Malignant melanoma, as a highly aggressive skin cancer, is strongly associated with
mutations in serine/threonine protein kinase B-RAF (BRAF, where RAF stands for rapidly …

Recent advances in oral and transdermal protein delivery systems

Y Yang, R Zhou, Y Wang, Y Zhang, J Yu… - Angewandte …, 2023 - Wiley Online Library
Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

[HTML][HTML] A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

Y Shi, A Lu, X Wang, Z Belhadj, J Wang… - … Pharmaceutica Sinica B, 2021 - Elsevier
The need for long-term treatments of chronic diseases has motivated the widespread
development of long-acting parenteral formulations (LAPFs) with the aim of improving drug …

Biomolecule-assisted green synthesis of nanostructured calcium phosphates and their biomedical applications

C Qi, S Musetti, LH Fu, YJ Zhu, L Huang - Chemical Society Reviews, 2019 - pubs.rsc.org
Calcium phosphates (CaPs) are ubiquitous in nature and vertebrate bones and teeth, and
have high biocompatibility and promising applications in various biomedical fields …