Abstract β-Hydroxybutyrate (βOHB), a ketone body, is oxidised as a brain fuel. Although its
contribution to energy metabolism in the healthy brain is minimal, it is an interesting …

Since it was first generally accepted that the two amino acids glutamate and GABA act as
principal neurotransmitters, several landmark discoveries relating to this function have been …

The central process in energy production is the oxidation of acetyl‐CoA to CO 2 by the
tricarboxylic acid (TCA, Krebs, citric acid) cycle. However, this cycle functions also as a …

Abstract Leif Hertz, MD, D. Sc.(honōris causā)(1930–2018), was one of the original and
noteworthy participants in the International Conference on Brain Energy Metabolism …

Diabetes is a metabolic disease afflicting millions of people worldwide. A substantial fraction
of world's total healthcare expenditure is spent on treating diabetes. Hypoglycemia is a …

Although oligodendrocytes constitute a significant proportion of cells in the central nervous
system (CNS), little is known about their intermediary metabolism. We have, therefore …

Parkinson's disease (PD) is the second most prominent neurodegenerative disease around
the world. Although it is known that PD is caused by the loss of dopaminergic cells in …

The first two publications dealing with the question of the cellular localization of the enzyme
pyruvate carboxylase (PC) which in the brain represents the most important metabolic …

Neuronal activity, astrocytic responses to this activity, and energy homeostasis are linked
together during baseline, conscious conditions, and short-term rapid activation (as occurs …

The astrocyte-neuron lactate shuttle (ANLS) is an essential metabolic support system that
uptakes glucose, stores it as glycogen in astrocytes, and provides glycogen-derived lactate …