Lung diseases affect the conducting airways, the gas exchange parenchyma, or both. As a
result, they have a high impact on patients' morbidity, and quality of life. Chronic obstructive …

Idiopathic pulmonary fibrosis (IPF) is a progressive pulmonary disease that is ultimately fatal.
Although the diagnosis of IPF has been revolutionized by high-resolution computed …

Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Purpose To develop a breathhold acquisition for regional mapping of ventilation and the
fractions of hyperpolarized xenon‐129 (Xe129) dissolved in tissue (lung parenchyma and …

Purpose We sought to develop and test a clinically feasible 1‐point Dixon, three‐
dimensional (3D) radial acquisition strategy to create isotropic 3D MR images of 129Xe in …

Magnetic‐resonance spectroscopy and imaging using hyperpolarized xenon‐129 show
great potential for evaluation of the most important function of the human lung‐‐gas …

Rationale and Objectives: The purpose of this review is to acquaint the reader with recent
advances in ultrashort echo time (UTE) magnetic resonance imaging (MRI) of the lung and …

Purpose To demonstrate the potential for high quality MRI of pulmonary ventilation using
naturally abundant xenon (NAXe) gas. Methods MRI was performed at 1.5 Tesla (T) and 3 T …

Although some central aspects of pulmonary function (ventilation and perfusion) are known
to be heterogeneous, the distribution of diffusive gas exchange remains poorly …

A variety of pulmonary pathologies, in particular interstitial lung diseases, are characterized
by thickening of the pulmonary blood–gas barrier, and this thickening results in reduced gas …