Bioactivity of dietary polyphenols: The role of metabolites
A polyphenol-rich diet protects against chronic pathologies by modulating numerous
physiological processes, such as cellular redox potential, enzymatic activity, cell proliferation …
physiological processes, such as cellular redox potential, enzymatic activity, cell proliferation …
Metabolic reprogramming and epigenetic modifications on the path to cancer
L Sun, H Zhang, P Gao - Protein & cell, 2022 - academic.oup.com
Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …
regulate each other, are among the well-known cancer hallmarks. Recent evidence …
[HTML][HTML] Curcumin: An epigenetic regulator and its application in cancer
T Ming, Q Tao, S Tang, H Zhao, H Yang, M Liu… - Biomedicine & …, 2022 - Elsevier
Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …
globally and is in great need of intense study on the pathogenic mechanism and effective …
Curcumin as an alternative epigenetic modulator: mechanism of action and potential effects
Curcumin (a polyphenolic compound in turmeric) is famous for its potent anti-inflammatory,
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …
anti-oxidant, and anti-cancer properties, and has a great potential to act as an epigenetic …
[HTML][HTML] Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review
Hydrogels have emerged as a versatile platform for a numerous biomedical application due
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …
to their ability to absorb a huge quantity of biofluids. In order to design hydrogels, natural …
Curcumin—from molecule to biological function
T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
DNA methyltransferases: a novel target for prevention and therapy
Cancer is the second leading cause of death in US. Despite the emergence of new, targeted
agents, and the use of various therapeutic combinations, none of the available treatment …
agents, and the use of various therapeutic combinations, none of the available treatment …
Multitargeting by curcumin as revealed by molecular interaction studies
Covering: up to early 2011 Curcumin (diferuloylmethane), the active ingredient in turmeric
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …
(Curcuma longa), is a highly pleiotropic molecule with anti-inflammatory, anti-oxidant …
Designing a broad-spectrum integrative approach for cancer prevention and treatment
Targeted therapies and the consequent adoption of “personalized” oncology have achieved
notable successes in some cancers; however, significant problems remain with this …
notable successes in some cancers; however, significant problems remain with this …
The role of epigenetic modifications in human cancers and the use of natural compounds as epidrugs: Mechanistic pathways and pharmacodynamic actions
A Bouyahya, H Mechchate, L Oumeslakht, I Zeouk… - Biomolecules, 2022 - mdpi.com
Cancer is a complex disease resulting from the genetic and epigenetic disruption of normal
cells. The mechanistic understanding of the pathways involved in tumor transformation has …
cells. The mechanistic understanding of the pathways involved in tumor transformation has …