A Guide to the Metabolic Pathways and Function of Metabolites Observed in Human Brain 1H Magnetic Resonance Spectra
CD Rae - Neurochemical research, 2014 - Springer
The current knowledge of the normal biochemistry of compounds that give rise to
resonances in human brain proton magnetic resonance spectra measureable at readily …
resonances in human brain proton magnetic resonance spectra measureable at readily …
Functional MRS studies of GABA and glutamate/Glx–A systematic review and meta-analysis
Functional magnetic resonance spectroscopy (fMRS) can be used to investigate
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
neurometabolic responses to external stimuli in-vivo, but findings are inconsistent. We …
In vivo mapping of brain myo-inositol
Myo-Inositol (MI) is one of the most abundant metabolites in the human brain located mainly
in glial cells and functions as an osmolyte. The concentration of MI is altered in many brain …
in glial cells and functions as an osmolyte. The concentration of MI is altered in many brain …
White matter damage, neuroinflammation, and neuronal integrity in HAND
A Alakkas, RJ Ellis, CWM Watson, A Umlauf… - Journal of …, 2019 - Springer
HIV-associated neurocognitive disorders (HANDs) persist even with virologic suppression
on combination antiretroviral therapy (cART), and the underlying pathophysiological …
on combination antiretroviral therapy (cART), and the underlying pathophysiological …
Magnetic resonance spectroscopy of the brain: a review of physical principles and technical methods
MH Buonocore, RJ Maddock - Reviews in the Neurosciences, 2015 - degruyter.com
Magnetic resonance spectroscopy (MRS) provides unique information about the
neurobiological substrates of brain function in health and disease. However, many of the …
neurobiological substrates of brain function in health and disease. However, many of the …
Brain region mapping using global metabolomics
Historically, studies of brain metabolism have been based on targeted analyses of a limited
number of metabolites. Here we present an untargeted mass spectrometry-based …
number of metabolites. Here we present an untargeted mass spectrometry-based …
[HTML][HTML] Potential for use of creatine supplementation following mild traumatic brain injury
There is significant overlap between the neuropathology of mild traumatic brain injury (mTBI)
and the cellular role of creatine, as well as evidence of neural creatine alterations after mTBI …
and the cellular role of creatine, as well as evidence of neural creatine alterations after mTBI …
Surface-enhanced spatially-offset Raman spectroscopy (SESORS) for detection of neurochemicals through the skull at physiologically relevant concentrations
AS Moody, TD Payne, BA Barth, B Sharma - Analyst, 2020 - pubs.rsc.org
Detection techniques for neurotransmitters that are rapid, label-free, and non-invasive are
needed to move towards earlier diagnosis of neurological disease. Surface-enhanced …
needed to move towards earlier diagnosis of neurological disease. Surface-enhanced …
Bilingualism is a long-term cognitively challenging experience that modulates metabolite concentrations in the healthy brain
Cognitively demanding experiences, including complex skill acquisition and processing,
have been shown to induce brain adaptations, at least at the macroscopic level, eg on brain …
have been shown to induce brain adaptations, at least at the macroscopic level, eg on brain …
Age-related differences in metabolites in the posterior cingulate cortex and hippocampus of normal ageing brain: a 1H-MRS study
H Reyngoudt, T Claeys, L Vlerick, S Verleden… - European journal of …, 2012 - Elsevier
OBJECTIVE: To study age-related metabolic changes in N-acetylaspartate (NAA), total
creatine (tCr), choline (Cho) and myo-inositol (Ins). MATERIALS AND METHODS: Proton …
creatine (tCr), choline (Cho) and myo-inositol (Ins). MATERIALS AND METHODS: Proton …