JNK-mediated closure of the Drosophila dorsal epidermis during embryogenesis is a well-
characterised model for morphogenesis. However, little is known about how JNK signalling …

The development of the Drosophila mesoderm is initiated by the basic helix‐loop‐helix
transcription factor twist. We identified a gene encoding a putative transcription factor, mes2 …

Tissue morphogenesis relies on proper differentiation of morphogenetic domains, adopting
specific cell behaviours. Yet, how signalling pathways interact to determine and coordinate …

In this thesis, I present the work I have done towards understanding the developmental
processes of Drosophila melanogaster, or the fruit fly, focusing specifically on the …

Patterning and wound healing are intricately connected mechanisms in organism
development and of significant importance for biomedicine. These mechanisms can be …

Os animais são revestidos pela epiderme e quando esta sofre algum dano tem de ser
rápida e eficazmente reparada. O processo de cicatrização é complexo e absolutamente …

Tissue engineering as a field emerged over a decade ago, and its aim was defined as
design and repair of tissues and organs. 1 Tissues are hierarchically structured, dynamic …