Flavonoids are considered beneficial, but they may exhibit pro-oxidative effects likely due to
metal reducing properties. For the first time, 24 structurally related flavonoids were …

Quercetin, a common flavonoid from human diet, is extensively metabolized. Its two
metabolites with the preserved flavonoid core were tested in detail for their interactions with …

Cobalt intoxication can occur after its release from metal-based prostheses, which is
generally clinically severe. Therefore, there is a need for the development of a cobalt …

Herein we report the synthesis of some new 1 H-1, 2, 4-triazole functionalized chromenols
(3a–3n) via tandem reactions of 1-(alkyl/aryl)-2-(1 H-1, 2, 4-triazole-1-yl) with salicylic …

Benzoic acids, which are commonly found in food, are also produced by human microbiota
from other dietary phenolics. The aim was to investigate the interactions of 8 food-related …

Novel spherical polymer nanoparticles were synthesized by hyperbranched
polyethylenimine (hPEI) and 6-hydroxy-2-naphthaldehyde (HNA) via Schiff base reaction …

Objectives Both pyridine and pyrano derivatives have been previously shown to possess
biologically relevant activity. In this study, we report the incorporation of these two scaffolds …

Background: Cobalt is an essential trace element, but it can also rarely cause cobalt toxicity
due to its release from cobalt-containing medical devices. Currently, there are no approved …

Background: Antiplatelet drugs represent the keystone in the treatment and prevention of
diseases of ischemic origin, including coronary artery disease. The current palette of drugs …

2, 3-Dehydrosilybin (DHS) was previously shown to chelate and reduce both copper and
iron ions. In this study, similar experiments with 2, 3-dehydrosilychristin (DHSCH) showed …