Microbial interactions within multiple-strain biological control agents impact soil-borne plant disease

B Niu, W Wang, Z Yuan, RR Sederoff… - Frontiers in …, 2020 - frontiersin.org
Major losses of crop yield and quality caused by soil-borne plant diseases have long
threatened the ecology and economy of agriculture and forestry. Biological control using …

Exploring structural diversity of microbe secondary metabolites using OSMAC strategy: A literature review

R Pan, X Bai, J Chen, H Zhang, H Wang - Frontiers in Microbiology, 2019 - frontiersin.org
Microbial secondary metabolites (MSMs) have played and continue to play a highly
significant role in the drug discovery and development process. Genetically, MSM chemical …

Fungal endophytes for sustainable crop production

BJJ Lugtenberg, JR Caradus… - FEMS microbiology …, 2016 - academic.oup.com
This minireview highlights the importance of endophytic fungi for sustainable agriculture and
horticulture production. Fungal endophytes play a key role in habitat adaptation of plants …

Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery

S Bertrand, N Bohni, S Schnee, O Schumpp… - Biotechnology …, 2014 - Elsevier
Microorganisms have a long track record as important sources of novel bioactive natural
products, particularly in the field of drug discovery. While microbes have been shown to …

Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters

T Netzker, J Fischer, J Weber, DJ Mattern… - Frontiers in …, 2015 - frontiersin.org
Microorganisms form diverse multispecies communities in various ecosystems. The high
abundance of fungal and bacterial species in these consortia results in specific …

Co-cultivation—A powerful emerging tool for enhancing the chemical diversity of microorganisms

A Marmann, AH Aly, W Lin, B Wang, P Proksch - Marine drugs, 2014 - mdpi.com
Marine-derived bacteria and fungi are promising sources of novel bioactive compounds that
are important for drug discovery programs. However, as encountered in terrestrial …

Mycotoxins in conversation with bacteria and fungi

N Venkatesh, NP Keller - Frontiers in microbiology, 2019 - frontiersin.org
An important goal of the mycotoxin research community is to develop comprehensive
strategies for mycotoxin control and detoxification. Although significant progress has been …

[HTML][HTML] Elicitation of secondary metabolism in actinomycetes

UR Abdelmohsen, T Grkovic, S Balasubramanian… - Biotechnology …, 2015 - Elsevier
Genomic sequence data have revealed the presence of a large fraction of putatively silent
biosynthetic gene clusters in the genomes of actinomycetes that encode for secondary …

Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules

BK Okada, MR Seyedsayamdost - FEMS microbiology reviews, 2017 - academic.oup.com
Natural products have traditionally served as a dominant source of therapeutic agents. They
are produced by dedicated biosynthetic gene clusters that assemble complex, bioactive …

Antimicrobial potentials of natural products against multidrug resistance pathogens: A comprehensive review

AH Elmaidomy, NH Shady, KM Abdeljawad… - RSC …, 2022 - pubs.rsc.org
Antibiotic resistance is one of the critical issues, describing a significant social health
complication globally. Hence, the discovery of novel antibiotics has acquired an increased …