Amniotic fluid (AF) is a complex substance essential to fetal well-being. This article reviews
recent discoveries and the current understanding of the origin and circulation of AF and its …

The advent of animal models of pediatric surgical diseases has not only allowed us to study
the etiology and pathogenesis of complex congenital anomalies but has also led to major …

Background/Purpose: Increasing evidence of physiologic in utero defecation supports the
hypothesis that bowel damage in gastroschisis may be meconium dependent. In this study …

BACKGROUND: The delayed onset of intestinal function in children with gastroschisis may
be because of the injurious effects of amniotic fluid on the exposed bowel. This has led to …

Background/Purpose: Contact with amniotic fluid (AF) causes intestinal damage in
gastroschisis, which has been shown to be caused by intraamniotic meconium. However …

OBJECTIVE To test the hypothesis that term gestation offers the best outcome. The
relationship between gestational age and the extent of bowel injury in fetuses with …

Introduction: We aimed to critically evaluate elective preterm delivery and immediate
abdominal wall closure and other techniques for the management of gastroschisis …

Background/Purpose: Urinary waste products in the amniotic fluid has been implicated as a
cause of intestinal damage (ID) in gastroschisis based on the fact that fetus urinates …

Neonates with gastroschisis have perivisceritis resulting from contact between the bowel
and amniotic fluid. Here, we characterized the mediators involved in this inflammatory …

Gastroschisis has been described precisely (if sporadically) for at least 300 years [1–4]. In
1953 Moore was the first to clearly differentiate gastroschisis from omphalocele [5]. Fear in …