Use of zebrafish in drug discovery toxicology
Unpredicted human safety events in clinical trials for new drugs are costly in terms of human
health and money. The drug discovery industry attempts to minimize those events with …
health and money. The drug discovery industry attempts to minimize those events with …
Towards a comprehensive catalog of zebrafish behavior 1.0 and beyond
AV Kalueff, M Gebhardt, AM Stewart, JM Cachat… - Zebrafish, 2013 - liebertpub.com
Zebrafish (Danio rerio) are rapidly gaining popularity in translational neuroscience and
behavioral research. Physiological similarity to mammals, ease of genetic manipulations …
behavioral research. Physiological similarity to mammals, ease of genetic manipulations …
ToxTrac: A fast and robust software for tracking organisms
A Rodriguez, H Zhang, J Klaminder… - Methods in Ecology …, 2018 - Wiley Online Library
Behavioural analysis based on video recording is becoming increasingly popular within
research fields such as; ecology, medicine, ecotoxicology and toxicology. However, the …
research fields such as; ecology, medicine, ecotoxicology and toxicology. However, the …
The developing utility of zebrafish models of neurological and neuropsychiatric disorders: A critical review
BD Fontana, NJ Mezzomo, AV Kalueff… - Experimental …, 2018 - Elsevier
Zebrafish (Danio rerio) have become a powerful tool in neuroscience research due to their
genetic tractability, molecular/physiological conservation, small body size, ease of …
genetic tractability, molecular/physiological conservation, small body size, ease of …
Exposure to microplastics decreases swimming competence in larval zebrafish (Danio rerio)
L Qiang, J Cheng - Ecotoxicology and environmental safety, 2019 - Elsevier
Microplastics have been frequently detected in both marine and freshwater ecosystems.
Their impact on aquatic organisms has raised much concern. This study investigated the …
Their impact on aquatic organisms has raised much concern. This study investigated the …
The potential for adverse effects in fish exposed to antidepressants in the aquatic environment
SL Gould, MJ Winter, WHJ Norton… - … Science & Technology, 2021 - ACS Publications
Antidepressants are one of the most commonly prescribed pharmaceutical classes for the
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …
treatment of psychiatric conditions. They act via modulation of brain monoaminergic …
Effects of the herbicide glyphosate on fish from embryos to adults: a review addressing behavior patterns and mechanisms behind them
AR Lopes, JS Moraes, CMG Martins - Aquatic Toxicology, 2022 - Elsevier
The use of agrochemicals has grown in recent years following the increase in agricultural
productivity, to eliminate weeds that can compromise crop yields. The intensive use of these …
productivity, to eliminate weeds that can compromise crop yields. The intensive use of these …
Measuring behavioral and endocrine responses to novelty stress in adult zebrafish
Several behavioral assays are currently used for high-throughput neurophenotyping and
screening of genetic mutations and psychotropic drugs in zebrafish (Danio rerio). In this …
screening of genetic mutations and psychotropic drugs in zebrafish (Danio rerio). In this …
Environmental enrichment for fish in captive environments: effects of physical structures and substrates
J Näslund, JI Johnsson - Fish and Fisheries, 2016 - Wiley Online Library
Structural environmental enrichment, that is, a deliberate addition of physical complexity to
the rearing environment, is sometimes utilized to reduce the expression of the undesirable …
the rearing environment, is sometimes utilized to reduce the expression of the undesirable …
Measuring anxiety in zebrafish: a critical review
C Maximino, TM de Brito, AW da Silva Batista… - Behavioural brain …, 2010 - Elsevier
Zebrafish are increasingly being used in behavioral neuroscience,
neuropsychopharmacology and neurotoxicology. Recently, behavioral screens used to …
neuropsychopharmacology and neurotoxicology. Recently, behavioral screens used to …