The hemostatic system as a modulator of atherosclerosis

JI Borissoff, HMH Spronk… - New England Journal of …, 2011 - Mass Medical Soc
The Hemostatic System as a Modulator of Atherosclerosis | NEJM Skip to main content NEJM
Group Follow Us Facebook Twitter Instagram YouTube LinkedIn Prepare to become a …

[HTML][HTML] Clinical review: Prothrombin complex concentrates-evaluation of safety and thrombogenicity

B Sørensen, DR Spahn, P Innerhofer, M Spannagl… - Critical Care, 2011 - Springer
Prothrombin complex concentrates (PCCs) are used mainly for emergency reversal of
vitamin K antagonist therapy. Historically, the major drawback with PCCs has been the risk …

Sustained prothrombotic changes in COVID-19 patients 4 months after hospital discharge

FA von Meijenfeldt, S Havervall, J Adelmeijer… - Blood …, 2021 - ashpublications.org
Patients with COVID-19 are at increased risk of thrombotic complications, despite the in-
hospital use of standard-or escalated-dose thromboprophylaxis. 1-3 As a result, numerous …

An imbalance of pro-vs anti-coagulation factors in plasma from patients with cirrhosis

A Tripodi, M Primignani, V Chantarangkul, A Dell'Era… - Gastroenterology, 2009 - Elsevier
BACKGROUND & AIMS: Patients with cirrhosis have an increased tendency to develop
thromboses despite the longer coagulation times of their plasma, compared with that of …

Mechanisms of estrogen-induced venous thromboembolism

SN Tchaikovski, J Rosing - Thrombosis research, 2010 - Elsevier
The use of oral contraceptives (OC) is a well established risk factor for venous thrombosis. It
has been known for many years that almost all haemostatic parameters ie plasma levels of …

[HTML][HTML] Thrombin generation assays for global evaluation of the hemostatic system: perspectives and limitations

RCF Duarte, CN Ferreira, DRA Rios, HJ Reis… - Revista brasileira de …, 2017 - SciELO Brasil
The existing techniques to evaluate hemostasis in clinical laboratories are not sensitive
enough to detect hypercoagulable and mild hypocoagulable states. Under different …

Thrombin generation testing in routine clinical practice: are we there yet?

JJ Van Veen, A Gatt, M Makris - British journal of haematology, 2008 - Wiley Online Library
Thrombin is the central enzyme in the coagulation cascade. Estimation of an individual's
potential to generate thrombin may correlate more closely with a hyper‐or hypo‐coagulable …

Thrombin generation tests

E Castoldi, J Rosing - Thrombosis research, 2011 - Elsevier
The recent development of semi-automated methods has revived interest in the thrombin
generation test, a global assay that measures the overall tendency of a plasma sample to …

[HTML][HTML] Enhanced thrombin generation in patients with cirrhosis‐induced coagulopathy

A Gatt, A Riddell, V Calvaruso, EG Tuddenham… - Journal of Thrombosis …, 2010 - Elsevier
Background: Prothrombin time (PT) and the international normalized ratio (INR) are still
routinely measured in patients with liver cirrhosis to 'assess' their bleeding risk despite the …

[HTML][HTML] Thrombin generation in patients with COVID-19 with and without thromboprophylaxis

E Campello, C Bulato, L Spiezia, A Boscolo… - Clinical Chemistry and …, 2021 - degruyter.com
Objectives Thrombin generation (TG) with and without thrombomodulin (TM) was evaluated
in COVID-19 patients with different disease severity and thromboprophylaxis regimen, in …