Anthracyclines have been important and effective treatments against a number of cancers
since their discovery. However, their use in therapy has been complicated by severe side …

Combination therapy and nanotechnology offer a promising therapeutic method in cancer
treatment. By improving drug's pharmacokinetics, nanoparticulate systems increase the …

Glioma is one of the primary malignant brain tumours in adults, with a poor prognosis.
Pharmacological reagents targeting glioma are limited to achieve the desired therapeutic …

Glioma is still hard to be treated due to their complex microenvironment. In this study, a gold
nanoparticle-based delivery system was developed. The system, An-PEG-DOX-AuNPs, was …

The adsorption mechanism of Doxorubicin (DOX) and Paclitaxel (PTX) mixture (1: 1) on
graphene (GRA) and graphene oxide (GOX) is determined using the molecular dynamics …

Doxorubicin (DOX) is a natural antibiotic with antineoplastic activity. It has been used for
over 40 years and remains one of the most used drugs in chemotherapy for a variety of …

Liposomal drug delivery for cancer therapy can be limited due to drug leakage in circulation.
Here, we develop a new method to enhance the stability of actively loaded liposomal …

One limiting factor of CAR T-cell therapy for treatment of solid cancers is the suppressive
tumor microenvironment (TME), which inactivates the function of tumor-infiltrating …

Phototherapy including photodynamic therapy (PDT) and photothermal therapy (PTT) has
attracted great attention. However, applications of some photosensitizers remain an obstacle …

A pH/redox-triggered mesoporous silica nanoparticle (MSN)-based nanoplatform has been
fabricated for doxorubicin/paclitaxel (DOX/PTX) codelivery. In this drug-delivery system …