MicroRNAs (miRNAs) are currently experiencing a renewed peak of attention not only as
diagnostics but also especially as highly promising novel targets or tools for clinical therapy …

Genetics play an increasingly important role in the risk stratification and management of
acute myeloid leukemia (AML) patients. Traditionally, AML classification and risk …

To clarify the cooperative roles of recurrently identified mutations and to establish a more
precise risk classification system in acute myeloid leukemia (AML), we comprehensively …

Some studies have suggested that cases of acute myeloid leukemia (AML) with low levels of
FLT3 internal tandem duplications (FLT3 ITD) do not have a worse prognosis if there is a …

Purpose To evaluate the impact of DNMT3A mutations on outcome in younger patients with
cytogenetic intermediate-risk acute myeloid leukemia. Patients and Methods Diagnostic …

Purpose: In acute myeloid leukemia (AML), alloreactive natural killer (NK) cells are crucial
mediators of immune responses after haploidentical stem cell transplantation. Allogeneic NK …

Acute myeloid leukemia (AML) is a heterogeneous disease. Until recently, treatment for
patients with AML was limited to induction chemotherapy with cytarabine and anthracycline …

Many genetic alterations that are associated with the prognosis of acute myeloid leukemia
(AML) have been identified, and several risk stratification systems based on the genetic …

The last decades have seen parallel improvements in chemotherapy‐based and
haematopoietic stem cell transplantation (HSCT) regimens for acute myeloid leukaemia …

The IKZF 1 gene at 7p12. 2 codes for IKAROS (also termed IKZF 1), an essential
transcription factor in haematopoiesis involved primarily in lymphoid differentiation. Its …