Publisher Summary This chapter discusses the role of plasminogen activators in various
biological processes. In specific, it describes two types of plasminogen activators—namely …

The plasmin–antiplasmin system plays a key role in blood coagulation and fibrinolysis.
Plasmin and α 2-antiplasmin are primarily responsible for a controlled and regulated …

The fibrinolytic system, more appropriately referred to as the plasminogen activator system,
controls not only the intravascular fibrin deposition but also participates in a wide variety of …

Cleavage of the HA polypeptide, the largest glycoprotein of the WSN strain of influenza
virus, to polypeptides HA1 plus HA2 occurs when influenza virus is grown in MDBK cells in …

Components of the plasminogen-plasmin system participate in a wide variety of physiologic
and pathologic processes, including tumor growth, invasion and metastasis, through their …

Bleomycin-induced lung injury is an established murine model of human pulmonary fibrosis.
Although procoagulant molecules (eg, tissue factor [TF]) and fibrinolytic components (eg …

The study of the plasminogen-plasmin system has, in the past, contributed much to the
understanding of fibrinolysis and thrombolysis. Attention is now focused on the role of the …

THERE is evidence that fibrinolytic enzymes are involved in the growth of tumours. It has
long been known that malignant tumours in culture lyse clotted plasma substrates1–3 …

A plasminogen activator secreted from human kidney cells was highly purified by affinity
chromatography on an anti-urokinase IgG-Sepharose column. The purified plasminogen …

Plasminogen was found to be present in bovine milk by crossreactivity between rabbit
antiserum to plasminogen and casein prepared from milk by acid precipitation. This result …