Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis
TRT Dagenais, NP Keller - Clinical microbiology reviews, 2009 - Am Soc Microbiol
Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …
Regulatory circuitry governing fungal development, drug resistance, and disease
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …
frequency of fungal infections in immunocompromised populations and the limited …
Aspergillus fumigatus and related species
JA Sugui, KJ Kwon-Chung… - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
The genus Aspergillus contains etiologic agents of aspergillosis. The clinical manifestations
of the disease range from allergic reaction to invasive pulmonary infection. Among the …
of the disease range from allergic reaction to invasive pulmonary infection. Among the …
What makes Aspergillus fumigatus a successful pathogen? Genes and molecules involved in invasive aspergillosis
A Abad, JV Fernández-Molina, J Bikandi… - Revista iberoamericana …, 2010 - Elsevier
Aspergillus fumigatus is an opportunistic pathogen that causes 90% of invasive aspergillosis
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …
(IA) due to Aspergillus genus, with a 50–95% mortality rate. It has been postulated that …
Aspergillus Galactosaminogalactan Mediates Adherence to Host Constituents and Conceals Hyphal β-Glucan from the Immune System
FN Gravelat, A Beauvais, H Liu, MJ Lee… - PLoS …, 2013 - journals.plos.org
Aspergillus fumigatus is the most common cause of invasive mold disease in humans. The
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
mechanisms underlying the adherence of this mold to host cells and macromolecules have …
The Aspergillus fumigatus cell wall integrity signaling pathway: drug target, compensatory pathways, and virulence
V Valiante, J Macheleidt, M Föge… - Frontiers in …, 2015 - frontiersin.org
Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …
infections with invasive growth in immunocompromised patients. The fungal cell wall (CW) …
Forced recycling of an AMA1-based genome-editing plasmid allows for efficient multiple gene deletion/integration in the industrial filamentous fungus Aspergillus …
T Katayama, H Nakamura, Y Zhang… - Applied and …, 2019 - Am Soc Microbiol
Filamentous fungi are used for food fermentation and industrial production of recombinant
proteins. They also serve as a source of secondary metabolites and are recently expected …
proteins. They also serve as a source of secondary metabolites and are recently expected …
Role of Trehalose Biosynthesis in Aspergillus fumigatus Development, Stress Response, and Virulence
Aspergillus fumigatus is a pathogenic mold which causes invasive, often fatal, pulmonary
disease in immunocompromised individuals. Recently, proteins involved in the biosynthesis …
disease in immunocompromised individuals. Recently, proteins involved in the biosynthesis …
Trehalose 6‐phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus …
S Puttikamonkul, SD Willger, N Grahl… - Molecular …, 2010 - Wiley Online Library
The trehalose biosynthesis pathway is critical for virulence in human and plant fungal
pathogens. In this study, we tested the hypothesis that trehalose 6‐phosphate phosphatase …
pathogens. In this study, we tested the hypothesis that trehalose 6‐phosphate phosphatase …
AbaA and WetA govern distinct stages of Aspergillus fumigatus development
L Tao, JH Yu - Microbiology, 2011 - microbiologyresearch.org
The opportunistic human pathogen Aspergillus fumigatus produces a massive number of
asexual spores (conidia) as the primary means of dispersal, survival, genome protection and …
asexual spores (conidia) as the primary means of dispersal, survival, genome protection and …