A decade of discovery and development of new anti-malarial medicines has led to a
renewed focus on malaria elimination and eradication. Changes in the way new anti …

Plasmodium vivax is the most widespread human malaria, putting 2.5 billion people at risk of
infection. Its unique biological and epidemiological characteristics pose challenges to …

BACKGROUND Miscarriage is the spontaneous loss of a pregnancy before 12 weeks (early
miscarriage) or from 12 to 24 weeks (late miscarriage) of gestation. Miscarriage occurs in …

Plasmodium vivax is an important cause of malaria, associated with a significant public
health burden. Whilst enhanced malaria-control activities have successfully reduced the …

Artemisinins are a family of sesquiterpene trioxane lactone anti-malarial agents originally
derived from Artemisia annua L. The anti-malarial action of artemisinins involves the …

Background Chloroquine is the first-line treatment for Plasmodium vivax malaria in most
endemic countries, but resistance is increasing. Monitoring of antimalarial efficacy is …

Vivax malaria threatens patients despite relatively low-grade parasitemias in peripheral
blood. The tenet of death as a rare outcome, derived from antiquated and flawed clinical …

Infection by bacteria, viruses, and parasites may lead to fetal death, organ injury, or limited
sequelae depending on the pathogen. Here, we consider the role of infection during …

One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …

COVID-19 prevention and treatment: A critical analysis of chloroquine and
hydroxychloroquine clinical pharmacology | PLOS Medicine Skip to main content …