Herpes simplex virus type 1 is a neurotropic herpesvirus that establishes latency within
sensory neurones. Following primary infection, the virus replicates productively within …

Herpes simplex viruses (HSV) can undergo a lytic infection in epithelial cells and a latent
infection in sensory neurons. During latency the virus persists until reactivation, which leads …

Principles of Virology, the leading virology textbook in use, is an extremely valuable and
highly informative presentation of virology at the interface of modern cell biology and …

Herpes simplex virus type 1 (HSV-1; human herpesvirus 1) and varicella-zoster virus (VZV;
human herpesvirus 3) are human neurotropic alphaherpesviruses that cause lifelong …

Herpes simplex virus (HSV) establishes a latent infection in peripheral neurons and can
periodically reactivate to cause disease. Reactivation can be triggered by a variety of stimuli …

Herpes simplex virus (HSV) persists in its human host and evades the immune response by
undergoing a latent infection in sensory neurons, from which it can reactivate periodically …

Like other alpha-herpesviruses, Herpes Simplex Virus Type 1 (HSV-1) possesses the ability
to establish latency in sensory ganglia as a non-integrated, nucleosome-associated …

An important question in virology is the mechanism (s) by which persistent viruses such as
the herpesviruses and human immunodeficiency virus (HIV) establish a latent infection in …

Herpes simplex virus type 1 (HSV-1) mutants that fail to express the viral immediate-early
protein ICP0 have a pronounced defect in viral gene expression and plaque formation in …

Like their cellular host counterparts, many invading viral pathogens must contend with,
modulate, and utilize the host cell's chromatin machinery to promote efficient lytic infection or …