Chimeric antigen receptor T‐cell therapy in multiple myeloma: a comprehensive review of current data and implications for clinical practice
RH Parikh, S Lonial - CA: A Cancer Journal for Clinicians, 2023 - Wiley Online Library
Multiple myeloma (MM) is a hematologic malignancy defined by the clonal proliferation of
transformed plasma cells. Despite tremendous advances in the treatment paradigm of MM, a …
transformed plasma cells. Despite tremendous advances in the treatment paradigm of MM, a …
CAR T-cell therapy in multiple myeloma: more room for improvement
PJ Teoh, WJ Chng - Blood Cancer Journal, 2021 - nature.com
The emergence of various novel therapies over the last decade has changed the therapeutic
landscape for multiple myeloma. While the clinical outcomes have improved significantly …
landscape for multiple myeloma. While the clinical outcomes have improved significantly …
Multiple myeloma therapy: emerging trends and challenges
Simple Summary Multiple myeloma (MM) is a frequent hematological malignancy
characterized by the uncontrolled growth of clonal plasma cells, primarily in the bone …
characterized by the uncontrolled growth of clonal plasma cells, primarily in the bone …
Determinants of response and mechanisms of resistance of CAR T-cell therapy in multiple myeloma
B-cell maturation antigen (BCMA)–specific chimeric antigen receptor (CAR) T cells have
substantial therapeutic potential in multiple myeloma (MM), but most patients eventually …
substantial therapeutic potential in multiple myeloma (MM), but most patients eventually …
Relapsed multiple myeloma demonstrates distinct patterns of immune microenvironment and malignant cell-mediated immunosuppression
Immunotherapy has shown efficacy in relapsed multiple myeloma (MM). However, these
therapies may depend on a functional tumor immune microenvironment (iTME) for their …
therapies may depend on a functional tumor immune microenvironment (iTME) for their …
2021 White Paper on Recent Issues in Bioanalysis: ISR for Biomarkers, Liquid Biopsies, Spectral Cytometry, Inhalation/Oral & Multispecific Biotherapeutics, Accuracy …
The 15th edition of the Workshop on Recent Issues in Bioanalysis (15th WRIB) was held on
27 September to 1 October 2021. Even with a last-minute move from in-person to virtual, an …
27 September to 1 October 2021. Even with a last-minute move from in-person to virtual, an …
Update on the current and future use of CAR‐T to treat multiple myeloma
Z Gahvari, M Brunner, T Schmidt… - European Journal of …, 2024 - Wiley Online Library
Chimeric antigen receptor T‐cell (CAR‐T) therapy has become an important intervention in
the management of relapsed and relapsed/refractory multiple myeloma (MM). Currently, B …
the management of relapsed and relapsed/refractory multiple myeloma (MM). Currently, B …
Promising antigens for the new frontier of targeted immunotherapy in multiple myeloma
SF Cho, L Xing, KC Anderson, YT Tai - Cancers, 2021 - mdpi.com
Simple Summary Defining the specificity and biological sequalae induced by receptors
differentiated expressed in multiple myeloma cells are critical for the development of …
differentiated expressed in multiple myeloma cells are critical for the development of …
BCMA-targeted biologic therapies: the next standard of care in multiple myeloma therapy
B Paul, C Rodriguez, SZ Usmani - Drugs, 2022 - Springer
With recent advances in myeloma therapy, patients can achieve long-term remissions, but
eventually relapses will occur. Triple-class refractory myeloma (disease that is refractory to …
eventually relapses will occur. Triple-class refractory myeloma (disease that is refractory to …
A review of chimeric antigen receptor T-cell therapy for myeloma and lymphoma
S Atrash, TK Moyo - OncoTargets and therapy, 2021 - Taylor & Francis
Collectively, hematological malignancies account for the fourth most common malignancy.
Myeloma and lymphoma are the most common types of hematological malignancies …
Myeloma and lymphoma are the most common types of hematological malignancies …