Pyrimidine: An elite heterocyclic leitmotif in drug discovery‐synthesis and biological activity
Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they
constitute an important class of natural and synthetic compounds exhibiting diverse useful …
constitute an important class of natural and synthetic compounds exhibiting diverse useful …
Medicinal plants used in traditional treatment of malaria in Ethiopia: a review of ethnomedicine, anti-malarial and toxicity studies
G Nigussie, M Wale - Malaria Journal, 2022 - Springer
Background Malaria is extremely common in Ethiopia, and it is one of the country's most
serious public health and economic problems. Traditional medicines have long been utilized …
serious public health and economic problems. Traditional medicines have long been utilized …
Indole-chalcone linked 1, 2, 3-triazole hybrids: Facile synthesis, antimicrobial evaluation and docking studies as potential antimicrobial agents
The design and synthesis of a new series of indole-chalcone linked 1, 2, 3-triazole hybrids
via Cu (Ι)-catalyzed azide-alkyne cycloaddition is reported. All the compounds (2, 4a–4e and …
via Cu (Ι)-catalyzed azide-alkyne cycloaddition is reported. All the compounds (2, 4a–4e and …
Click reaction inspired synthesis, antimicrobial evaluation and in silico docking of some pyrrole-chalcone linked 1, 2, 3-triazole hybrids
The discovery of small organic molecules as new antimicrobial agents is a promising
strategy for encountering the problem of multidrug-resistant microbial strains. In an attempt …
strategy for encountering the problem of multidrug-resistant microbial strains. In an attempt …
Significance of chalcone scaffolds in medicinal chemistry
Chalcone is a simple naturally occurring α, β-unsaturated ketone with biological importance,
which can also be easily synthesized in laboratories by reaction between two aromatic …
which can also be easily synthesized in laboratories by reaction between two aromatic …
[HTML][HTML] Synthesis, characterization, docking study and biological evaluation of new chalcone, pyrazoline, and pyrimidine derivatives as potent antimalarial …
MM Alidmat, M Khairuddean, NM Norman… - Arabian Journal of …, 2021 - Elsevier
Malaria is a protozoan disease caused by a unicellular parasite named Plasmodium
(Phylum-Apicomplexa). World Health Organization has estimated roughly fifty percent of the …
(Phylum-Apicomplexa). World Health Organization has estimated roughly fifty percent of the …
Plant alkaloids: production, extraction, and potential therapeutic properties
Alkaloids are a type of secondary metabolites that can be found in different parts of plants.
This group of compounds is diverse and can be divided into nine subgroups: pyridine …
This group of compounds is diverse and can be divided into nine subgroups: pyridine …
[PDF][PDF] Investigation of amino chalcone derivatives as anti-proliferative agents against MCF-7 breast cancer cell lines-DFT, molecular docking and pharmacokinetics …
OE Oyeneyin, T Abayomi, N Ipinloju… - Advanced Journal of …, 2021 - researchgate.net
The World Health Organization (WHO) has labeled cancer as a major threat to human
health, it is the second most lethal disease after cardiovascular diseases and has resulted in …
health, it is the second most lethal disease after cardiovascular diseases and has resulted in …
A Comprehensive Review of The Molecular Dynamic Study Of Chalcones, Coumarins and Chromones as Selective MAO‐B Inhibitors [2015‐Till Date]
R Rachel Thomas, N Chandran… - …, 2024 - Wiley Online Library
Molecular dynamics (MD) simulation is an in silico method used in the biomolecular level of
research to study how the protein interacts with the target with time. It provides a detailed …
research to study how the protein interacts with the target with time. It provides a detailed …
The crystal structure of (E)-1-(4-aminophenyl)-3-(p-tolyl)prop-2-en-1-one, C16H15NO
J Zhang, J Lv, J Wang - Zeitschrift für Kristallographie-New Crystal …, 2022 - degruyter.com
The crystal structure of (E)-1-(4-aminophenyl)-3-(p-tolyl)prop-2-en-1-one, C16H15NO Skip to
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