Background Chronic respiratory disease causes substantial global morbidity and mortality.
The contribution of pulmonary tuberculosis to the aetiology of chronic respiratory disease is …

Background People with non‐cystic fibrosis bronchiectasis commonly experience chronic
cough and sputum production, features that may be associated with progressive decline in …

CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary …

Bronchiectasis is a multidimensional disease and, therefore, its severity or prognosis cannot
be adequately quantified by analysing one single variable. The objective of the present …

Importance Macrolide antibiotics have been shown beneficial in cystic fibrosis (CF) and
diffuse panbronchiolitis, and earlier findings also suggest a benefit in non-CF …

Background Azithromycin is a macrolide antibiotic with anti-inflammatory and
immunomodulatory properties. We tested the hypothesis that azithromycin would decrease …

Rationale: Chronic infection with Pseudomonas aeruginosa is associated with an increased
exacerbation frequency, a more rapid decline in lung function, and increased mortality in …

Rationale: Characterization of bacterial populations in infectious respiratory diseases will
provide improved understanding of the relationship between the lung microbiota, disease …

Background Bronchiectasis remains a major public health problem, but factors influencing
its natural history are not well characterized. The objective of our study was to explore …

Rationale: Bronchiectasis is a chronic debilitating disease with few evidence-based long-
term treatments. Objectives: A randomized controlled trial assessing the efficacy of …