Thiophenes are one of the abundantly found heterocyclic ring systems in many biologically
active compounds. Moreover, various substituted thiophenes exert numerous …

The reaction of the cyclopenta [b] thiophene derivative 3 with phenylisothiocyanate4 gave
thiourea derivative 5. The latter was reacted with the active methylene reagents 2a, b and 7 …

On the basis of the proven activity of thieno [2, 3‐b] pyridines as anticancer, we have
designed to synthesize a novel several heterocyclic compounds utilizing thieno [2, 3‐b] …

The reaction of either cyclohexanone or cyclopentanone with cyanoacetylhydrazine and
elemental sulfur gave the 2-aminocycloalkeno [b] thiophene derivatives 3a and 3b …

The present work deals with the synthesis of 2-cyano-N′-(3-(2-(2-cyanoacetyl) hydrazinyl)
cyclohex-2-en-1-ylidene) acetohydrazide 3 that used as a key precursor in the manufacture …

Reaction of N4-(4-chlorophenyl)-1, 3-thiazole-2, 4-diamine 1 with ammonium thiocyanate,
phenyl isothiocyanate, acetic anhydride, phenacyl bromide, 2-chloro-N-(4-chlorophenyl) …

The reaction of cyclopentanone with either malononitrile or ethyl cyanoacetate gave the
corresponding condensated products. The latter underwent some heterocyclic reactions to …