[HTML][HTML] CLIP and complementary methods
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
Revealing protein–lncRNA interaction
F Ferre, A Colantoni… - Briefings in …, 2016 - academic.oup.com
Long non-coding RNAs (lncRNAs) are associated to a plethora of cellular functions, most of
which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs …
which require the interaction with one or more RNA-binding proteins (RBPs); similarly, RBPs …
Sequences enriched in Alu repeats drive nuclear localization of long RNAs in human cells
Y Lubelsky, I Ulitsky - Nature, 2018 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as key parts of multiple cellular pathways,
but their modes of action and how these are dictated by sequence remain unclear. lncRNAs …
but their modes of action and how these are dictated by sequence remain unclear. lncRNAs …
Dynamic characterization and interpretation for protein-RNA interactions across diverse cellular conditions using HDRNet
RNA-binding proteins play crucial roles in the regulation of gene expression, and
understanding the interactions between RNAs and RBPs in distinct cellular conditions forms …
understanding the interactions between RNAs and RBPs in distinct cellular conditions forms …
Prediction of RNA-protein sequence and structure binding preferences using deep convolutional and recurrent neural networks
Background RNA regulation is significantly dependent on its binding protein partner, known
as the RNA-binding proteins (RBPs). Unfortunately, the binding preferences for most RBPs …
as the RNA-binding proteins (RBPs). Unfortunately, the binding preferences for most RBPs …
A deep learning framework for modeling structural features of RNA-binding protein targets
RNA-binding proteins (RBPs) play important roles in the post-transcriptional control of
RNAs. Identifying RBP binding sites and characterizing RBP binding preferences are key …
RNAs. Identifying RBP binding sites and characterizing RBP binding preferences are key …
Specificity and nonspecificity in RNA–protein interactions
E Jankowsky, ME Harris - Nature reviews Molecular cell biology, 2015 - nature.com
To fully understand the regulation of gene expression, it is critical to quantitatively define
whether and how RNA-binding proteins (RBPs) discriminate between alternative binding …
whether and how RNA-binding proteins (RBPs) discriminate between alternative binding …
Predicting dynamic cellular protein–RNA interactions by deep learning using in vivo RNA structures
Interactions with RNA-binding proteins (RBPs) are integral to RNA function and cellular
regulation, and dynamically reflect specific cellular conditions. However, presently available …
regulation, and dynamically reflect specific cellular conditions. However, presently available …
Predicting RNA–protein binding sites and motifs through combining local and global deep convolutional neural networks
X Pan, HB Shen - Bioinformatics, 2018 - academic.oup.com
Motivation RNA-binding proteins (RBPs) take over 5–10% of the eukaryotic proteome and
play key roles in many biological processes, eg gene regulation. Experimental detection of …
play key roles in many biological processes, eg gene regulation. Experimental detection of …
The lncRNA landscape of breast cancer reveals a role for DSCAM-AS1 in breast cancer progression
Molecular classification of cancers into subtypes has resulted in an advance in our
understanding of tumour biology and treatment response across multiple tumour types …
understanding of tumour biology and treatment response across multiple tumour types …