Role of platelets in neutrophil extracellular trap (NET) production and tissue injury
SJ Kim, CN Jenne - Seminars in immunology, 2016 - Elsevier
In addition to their well-known role as the cellular mediator of thrombosis, numerous studies
have identified key roles for platelets during various disease processes. Importantly …
have identified key roles for platelets during various disease processes. Importantly …
Emerging role of high mobility group box-1 in thrombosis-related diseases
H Wu, R Li, LG Pei, ZH Wei, LN Kang, L Wang… - Cellular Physiology and …, 2018 - karger.com
High mobility group box-1 (HMGB-1), a typical damage-associated molecular pattern protein
released from various cells, was first identified in 1973. It is usually stored in the nuclei of …
released from various cells, was first identified in 1973. It is usually stored in the nuclei of …
Optimizing transfusion strategies in damage control resuscitation: current insights
TH Pohlman, AM Fecher… - Journal of blood …, 2018 - Taylor & Francis
From clinical and laboratory studies of specific coagulation defects induced by injury,
damage control resuscitation (DCR) emerged as the most effective management strategy for …
damage control resuscitation (DCR) emerged as the most effective management strategy for …
[HTML][HTML] Blockade of extracellular high-mobility group box 1 attenuates systemic inflammation and coagulation abnormalities in rats with acute traumatic coagulopathy
L Xu, K Zhao, X Shen, X Fan, K Ding… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
Background As an extracellularly released mediator, high-mobility group box 1 (HMGB1)
initiates sterile inflammation following severe trauma. Serum HMGB1 levels correlate well …
initiates sterile inflammation following severe trauma. Serum HMGB1 levels correlate well …
Type 1 interferon aggravates lipopolysaccharide-induced sepsis through upregulating Caspase-11 and Gasdermin D
Y Wang, X Zhang, Y Guo, X Li, G Guo, Z Niu… - Journal of physiology …, 2021 - Springer
This study aimed to investigate the mechanism of type I interferon (IFN) in aggravating
sepsis in bacterial infection, focusing on the roles of Caspase-11 (Casp11) and Gasdermin …
sepsis in bacterial infection, focusing on the roles of Caspase-11 (Casp11) and Gasdermin …
Role of plasma high mobility group box-1 in disseminated intravascular coagulation with leukemia
M Wang, H Mei, H Kou, J Deng, H Wang, T Guo… - Thrombosis Research, 2015 - Elsevier
Introduction High mobility group box 1 (HMGB1) is a DNA-binding protein which can act as a
proinflammatory cytokine when released by necrotic cells, monocytes or macrophages. It …
proinflammatory cytokine when released by necrotic cells, monocytes or macrophages. It …
High-mobility group box-1 protein determination in postmortem samples
C Palmiere, M Augsburger, P Mangin - Forensic science international, 2014 - Elsevier
The aims of this study were to assess whether high-mobility group box-1 protein can be
determined in biological fluids collected during autopsy and evaluate the diagnostic …
determined in biological fluids collected during autopsy and evaluate the diagnostic …
High Mobility Group Box-1 as a Candidate Biomarker of Portal Vein Thrombosis in Patients with Hepatocellular Carcinoma
M Perazzi, R Piffero, R Minisini, S Gaia, E Rolle… - 2023 - preprints.org
Background High Mobility Group Box-1 (HMGB-1) is implicated in the pathogenesis of
thrombosis and cancer. In the present study, we aimed to evaluate its potential role as a …
thrombosis and cancer. In the present study, we aimed to evaluate its potential role as a …