Cardiovascular disease and breast cancer: where these entities intersect: a scientific statement from the American Heart Association

LS Mehta, KE Watson, A Barac, TM Beckie, V Bittner… - Circulation, 2018 - Am Heart Assoc
Cardiovascular disease (CVD) remains the leading cause of mortality in women, yet many
people perceive breast cancer to be the number one threat to women's health. CVD and …

Cardiotoxicity of anticancer treatments: epidemiology, detection, and management

G Curigliano, D Cardinale, S Dent… - CA: a cancer journal …, 2016 - Wiley Online Library
Answer questions and earn CME/CNE Cancer and heart disease are the leading causes of
morbidity and mortality in the industrialized world. Modern treatment strategies have led to …

Multidisciplinary approach to novel therapies in cardio-oncology research (MANTICORE 101–Breast): a randomized trial for the prevention of trastuzumab-associated …

E Pituskin, JR Mackey, S Koshman, D Jassal… - Journal of clinical …, 2017 - ascopubs.org
Purpose The primary toxicity of trastuzumab therapy for human epidermal growth factor
receptor 2–overexpressing (HER2-positive) breast cancer is dose-independent cardiac …

Cardio-oncology: an update on cardiotoxicity of cancer-related treatment

CG Lenneman, DB Sawyer - Circulation research, 2016 - Am Heart Assoc
Through the success of basic and disease-specific research, cancer survivors are one of the
largest growing subsets of individuals accessing the healthcare system. Interestingly …

Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment: a retrospective cohort study

EJA Bowles, R Wellman, HS Feigelson… - Journal of the …, 2012 - academic.oup.com
Background Clinical trials demonstrated that women treated for breast cancer with
anthracycline or trastuzumab are at increased risk for heart failure and/or cardiomyopathy …

Independent and incremental value of deformation indices for prediction of trastuzumab-induced cardiotoxicity

K Negishi, T Negishi, JL Hare, BA Haluska… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Assessment of left ventricular systolic function is necessary during
trastuzumab-based chemotherapy because of potential cardiotoxicity. Deformation indices …

Trastuzumab-induced cardiotoxicity: clinical and prognostic implications of troponin I evaluation

D Cardinale, A Colombo, R Torrisi… - Journal of Clinical …, 2010 - ascopubs.org
Purpose Treatment of breast cancer with trastuzumab is complicated by cardiotoxicity in up
to 34% of the patients. In most patients, trastuzumab-induced cardiotoxicity (TIC) is …

Cardiotoxicity of chemotherapeutic agents and radiotherapy-related heart disease: ESMO Clinical Practice Guidelines

D Bovelli, G Plataniotis, F Roila - Annals of oncology, 2010 - annalsofoncology.org
New anticancer therapies have led to a long life expectancy for many patients; however,
treatment-related comorbidities have become an issue for long-term cancer survivors …

Cancer therapy–induced cardiac toxicity in early breast cancer: addressing the unresolved issues

MG Khouri, PS Douglas, JR Mackey, M Martin… - Circulation, 2012 - Am Heart Assoc
The landscape of early breast cancer has changed dramat-ically with significant
advancements in early screening and diagnosis and curative-intent therapies. Indeed …

Pathophysiological mechanisms of cardiotoxicity in chemotherapeutic agents

AM Chaulin, OE Abashina… - Russian Open Medical …, 2020 - cyberleninka.ru
Certain success has been achieved in the treatment of cancer due to the development of
various effective chemotherapeutic drugs. However, an increase in their effectiveness …