As early as the 1920s, and subsequently in the 1959 Build and Blood Pressure Study (S1. 5-
1) of almost 5 million adults insured between 1934 and 1954, a strong direct relationship …

Longstanding hypertension ultimately leads to heart failure (HF), and, as a consequence
most patients with HF have a history of hypertension. Conversely, absence of hypertension …

Background: Recent sham-controlled randomized clinical trials have confirmed the safety
and efficacy of catheter-based renal denervation (RDN). Long-term safety and efficacy data …

This review and update focuses on the clinical features of hydrochlorothiazide (HCTZ), the
thiazide-like agents chlorthalidone (CTDN) and indapamide (INDAP), potassium-sparing …

Diuretics have been recommended as first-line treatment of hypertension and are also
valuable in the management of hypervolemia and electrolyte disorders. This review …

This acclaimed text promotes healthy aging by demonstrating how health practitioners,
program developers, and policymakers can prevent or manage disease and make large …

BACKGROUND The prevalence of hypertension among elderly persons has been assessed
in several circumscribed studies scattered across Brazil, and no representative data about …

Background: optimal blood pressure targets in older adults are controversial. Objective: to
investigate whether the relation of blood pressure with mortality in older adults varies by …

The pharmaceutical industry has significantly contributed to improving human health. Drugs
have been attributed to both increasing life expectancy and decreasing health care costs …

High blood pressure (HBP) or hypertension (HTN) is one of the leading causes of
cardiovascular (CV) morbidity and mortality throughout the world. Despite this fact, there is …