Tinkering with translation: protein synthesis in virus-infected cells
D Walsh, MB Mathews, I Mohr - Cold Spring Harbor …, 2013 - cshperspectives.cshlp.org
Viruses are obligate intracellular parasites, and their replication requires host cell functions.
Although the size, composition, complexity, and functions encoded by their genomes are …
Although the size, composition, complexity, and functions encoded by their genomes are …
FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis
A Krueger, S Baumann, PH Krammer… - Molecular and cellular …, 2001 - Taylor & Francis
Cell death is executed along several pathways. Apart from necrotic cell death occurring
upon tissue injury, several distinct types of apoptosis have been observed. Apoptosis, or …
upon tissue injury, several distinct types of apoptosis have been observed. Apoptosis, or …
Small molecules targeting viral RNA
T Hermann - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
Highly conserved noncoding RNA (ncRNA) elements in viral genomes and transcripts offer
new opportunities to expand the repertoire of drug targets for the development of …
new opportunities to expand the repertoire of drug targets for the development of …
Searching for IRES
The cell has many ways to regulate the production of proteins. One mechanism is through
the changes to the machinery of translation initiation. These alterations favor the translation …
the changes to the machinery of translation initiation. These alterations favor the translation …
[HTML][HTML] Endothelial infection with KSHV genes in vivo reveals that vGPCR initiates Kaposi's sarcomagenesis and can promote the tumorigenic potential of viral latent …
S Montaner, A Sodhi, A Molinolo, TH Bugge, ET Sawai… - Cancer cell, 2003 - cell.com
The Kaposi's sarcoma herpesvirus (KSHV) has been identified as the etiologic agent of
Kaposi's sarcoma (KS), but initial events leading to KS development remain unclear …
Kaposi's sarcoma (KS), but initial events leading to KS development remain unclear …
KSHV vFLIP is essential for the survival of infected lymphoma cells
I Guasparri, SA Keller, E Cesarman - The Journal of experimental …, 2004 - rupress.org
Primary effusion lymphomas (PELs) associated with infection by the Kaposi's sarcoma–
associated herpesvirus (KSHV/HHV-8) have constitutive nuclear factor (NF)–κB activity that …
associated herpesvirus (KSHV/HHV-8) have constitutive nuclear factor (NF)–κB activity that …
Kaposi sarcoma-associated herpesvirus (KSHV): molecular biology and oncogenesis
KW Wen, B Damania - Cancer letters, 2010 - Elsevier
Kaposi sarcoma-associated herpesvirus (KSHV) is a double-stranded DNA herpesvirus
belonging to the γ-herpesvirinae subfamily. KSHV has been associated with the …
belonging to the γ-herpesvirinae subfamily. KSHV has been associated with the …
A time to kill: viral manipulation of the cell death program
S Hay, G Kannourakis - Journal of General Virology, 2002 - microbiologyresearch.org
Many viruses have as part of their arsenal the ability to modulate the apoptotic pathways of
the host. It is counter-intuitive that such simple organisms would be efficient at regulating this …
the host. It is counter-intuitive that such simple organisms would be efficient at regulating this …
KSHV infection and the pathogenesis of Kaposi's sarcoma
D Ganem - Annu. Rev. Pathol. Mech. Dis., 2006 - annualreviews.org
Kaposi's sarcoma (KS) has long been suspected of having an infectious etiology on the
basis of its unusual epidemiology, histopathology, and natural history. Nearly a decade ago …
basis of its unusual epidemiology, histopathology, and natural history. Nearly a decade ago …
KSHV vFLIP binds to IKK-γ to activate IKK
When expressed in heterologous cells, the viral FLIP protein (vFLIP) of Kaposi's-sarcoma-
associated herpesvirus (KSHV) has been reported both to block Fas-mediated apoptosis …
associated herpesvirus (KSHV) has been reported both to block Fas-mediated apoptosis …