Uric acid and cognitive decline: a double-edge sword?

A Latourte, T Bardin, P Richette - Current opinion in rheumatology, 2018 - journals.lww.com
We lack strong evidence for an association between low SUA level and cognitive decline
over time. Conversely, high SUA level might increase the cerebrovascular burden and the …

Gout is not associated with a lower risk of Parkinson's disease: a systematic review and meta-analysis

P Ungprasert, N Srivali, C Thongprayoon - Parkinsonism & related …, 2015 - Elsevier
Background Uratic acid is a potent anti-oxidant and hyperuricemia is well-linked to a lower
risk of Parkinson's disease (PD), one of the most common neurodegenerative disorders …

Serum uric acid and its association with longitudinal cognitive change among urban adults

MA Beydoun, JA Canas, GA Dore… - Journal of …, 2016 - content.iospress.com
Uric acid, a waste metabolite among humans, was linked to various cognitive outcomes. We
describe sex and age-group specific associations of baseline serum uric acid (SUA base) …

A prospective study on the association between uric acid and cognitive function among middle-aged and older Chinese

T Wang, Y Wu, Y Sun, L Zhai… - Journal of Alzheimer's …, 2017 - content.iospress.com
Background: Uric acid (UA) is a powerful antioxidant that may have neuroprotective
properties, yet it is also a risk factor of vascular disease that predisposes individuals to …

Relationship between serum uric acid level and mild cognitive impairment in Chinese community elderly

M Liu, J Wang, J Zeng, Y He - BMC neurology, 2017 - Springer
Background To evaluate the association between SUA levels within a normal to high range
and the risk of mild cognitive impairment (MCI) among community elderly. Methods The …

[HTML][HTML] Correlation of serum uric acid, cystatin C and high-sensitivity C-reactive protein with cognitive impairment in lacunar cerebral infarction

F Wanggong, J Xiang, S Yang, W Zhang… - American journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To study the correlation of serum uric acid (UA), cystatin C (Cys-C) and high-
sensitivity C-reactive protein (hs-CRP) with cognitive impairment in lacunar cerebral …

U-shaped association between serum uric acid levels and cognitive functions in patients with type 2 diabetes: a cross-sectional study

R Huang, S Tian, J Han, H Lin, D Guo… - Journal of …, 2019 - content.iospress.com
Background: Serum uric acid (SUA) is a natural antioxidant that may exert neuroprotective
effects against neurodegenerative diseases. The relationship between uric acid and …

Hyperuricemia and dementia–a case-control study

B Engel, W Gomm, K Broich, W Maier, K Weckbecker… - bmc neurology, 2018 - Springer
Background There is evidence that uric acid may have antioxidant and neuroprotective
effects and might therefore alter the risk for neurodegenerative diseases such as dementia …

Uric acid is associated with vascular dementia in Chinese population

Y Xu, Q Wang, R Cui, K Lu, Y Liu, Y Zhao - Brain and behavior, 2017 - Wiley Online Library
Objective Mounting evidence suggests that oxidative stress is involved in the pathogenesis
of vascular dementia (VD). Uric acid (UA) has long been implicated as a critical cause of …

Association between serum uric acid concentrations and grip strength: is there effect modification by age?

E García-Esquinas, F Rodríguez-Artalejo - Clinical Nutrition, 2018 - Elsevier
Background Given that some of the deleterious effects of uric acid (UA) on health are greater
in younger than in older subjects, and that age is strongly associated with skeletal muscle …