Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …

Simple Summary Macrophages are a specialized immune cell type found in both
invertebrates and vertebrates. Versatile in functionality, macrophages carry out important …

As a key step of tumor lymphatic metastasis, lymphangiogenesis is regulated by VEGFC‐
VEGFR3 signaling pathway mediated by immune cells, mainly macrophages, in the tumor …

Glioblastoma (GBM) is a common and highly malignant primary tumor of the central nervous
system in adults. Ever more recent papers are focusing on understanding the role of the …

Diffuse midline glioma (DMG), formerly called diffuse intrinsic pontine glioma (DIPG), is a
high-grade malignant pediatric brain tumor with a near-zero survival rate. To date, only …

The tumor microenvironment is overwhelmingly dictated by macrophages, intimately
affiliated with tumors, exercising pivotal roles in multiple processes, including angiogenesis …

The glioma tumor microenvironment plays a crucial role in the development, occurrence,
and treatment of gliomas. Glioma-associated macrophages (GAMs) are the most widely …

Background and aim: Ever since the discovery of tumor-associated immune cells, there has
been growing interest in the understanding of the mechanisms underlying the crosstalk …

In glioblastoma (GBM), the interplay of different immune cell subtypes, cytokines, and/or
drugs shows high context-dependencies. Interrelations between the routinely applied …

Glioblastoma multiforme (GBM) is recognized as the most aggressive and malignant form of
brain cancer, characterized by a highly heterogeneous phenotype, poor prognosis, and a …