Phytochemicals as treatment for allergic asthma: Therapeutic effects and mechanisms of action

SV Jasemi, H Khazaei, MR Morovati, T Joshi, IY Aneva… - Phytomedicine, 2024 - Elsevier
Background Allergic asthma is an inflammatory disease caused by the immune system's
reaction to allergens, inflammation and narrowing of the airways, and the production of more …

A review of the use of antioxidants in bovine sperm preparation protocols

V Sapanidou, MP Tsantarliotou… - Animal Reproduction …, 2023 - Elsevier
Reactive oxygen species (ROS) and oxidative stress (OS), the imbalance between the
production of free radicals and the cellular antioxidant defenses, are discussed in relation to …

Mechanism of antitumor effects of saffron in human prostate cancer cells

M Khan, K Hearn, C Parry, M Rashid, H Brim… - Nutrients, 2023 - mdpi.com
Prostate cancer is the most common cancer and the second leading cause of cancer deaths
among men in the USA. Several studies have demonstrated the antitumor properties of …

Multifaceted roles of crocin, phytoconstituent of Crocus sativus Linn. In cancer treatment: An expanding horizon

Y Mishra, V Mishra - South African Journal of Botany, 2023 - Elsevier
Despite the proliferation of medications and therapies for cancer patients, cancer is an
illness that significantly influences the expectancy and quality of life. Globally, there is a …

Therapeutic implications of crocin in Parkinson's disease: A review of preclinical research

A Goyal, A Verma, A Agrawal, N Dubey… - Chemical Biology & …, 2023 - Wiley Online Library
Parkinson's disease is among the most common forms of neurodegenerative illness, with
present treatment being primarily symptomatic and frequently coming with substantial …

Effects of Supplementation with the Standardized Extract of Saffron (affron®) on the Kynurenine Pathway and Melatonin Synthesis in Rats

M De la Fuente Muñoz, M Román-Carmena, S Amor… - Antioxidants, 2023 - mdpi.com
Melatonin is a hormone that regulates sleep–wake cycles and is mainly synthesized in the
pineal gland from tryptophan after its conversion into serotonin. Under normal conditions …

The therapeutic potential of traditional Chinese medicine in depression: focused on the modulation of neuroplasticity

S Lv, N Yang, Y Lu, G Zhang, X Zhong, Y Cui… - Frontiers in …, 2024 - frontiersin.org
Depression, a mood disorder characterized by a persistent low mood and lack of enjoyment,
is considered the leading cause of non-fatal health losses worldwide. Neuroplasticity refers …

[HTML][HTML] Crocin Protects the 661W Murine Photoreceptor Cell Line against the Toxic Effects of All-Trans-Retinal

B Yang, K Yang, J Chen, Y Wu - International Journal of Molecular …, 2024 - mdpi.com
Age-related macular degeneration (AMD) is a common disease contributing to vision loss in
the elderly. All-trans-retinal (atRAL) is a retinoid in the retina, and its abnormal accumulation …

Construction of a high-efficiency GjCCD4a mutant and its application for de novo biosynthesis of five crocins in Escherichia coli

S Li, Z Zhou, Y Li, Y Hu, Z Huang, G Hu, Y Wang… - International Journal of …, 2024 - Elsevier
Crocins are bioactive natural products that rarely exist in plants. High costs and resource
shortage severely limit its development and application. Synthetic biology studies on crocins …

Molecular and Behavioral Neuroprotective Effects of Clavulanic Acid and Crocin in Haloperidol-Induced Tardive Dyskinesia in Rats

P Shoae-Hagh, BM Razavi, HR Sadeghnia… - Molecular …, 2024 - Springer
Clavulanic acid (ClvA), a beta-lactamase inhibitor, is being explored for its significant
neuroprotective potential. The effects of ClvA were assessed both individually and in …