Metal drugs and the anticancer immune response

B Englinger, C Pirker, P Heffeter, A Terenzi… - Chemical …, 2018 - ACS Publications
The immune system deploys a multitude of innate and adaptive mechanisms not only to
ward off pathogens but also to prevent malignant transformation (“immune surveillance”) …

Tolerability and safety of rituximab (MabThera®)

E Kimby - Cancer treatment reviews, 2005 - Elsevier
Rituximab, a human/mouse chimeric anti-CD20 antibody, has become part of standard
therapy for patients with CD20-expressing B-cell lymphoma, and is currently under …

[HTML][HTML] Axicabtagene ciloleucel CAR T-cell therapy in refractory large B-cell lymphoma

SS Neelapu, FL Locke, NL Bartlett… - … England Journal of …, 2017 - Mass Medical Soc
Background In a phase 1 trial, axicabtagene ciloleucel (axi-cel), an autologous anti-CD19
chimeric antigen receptor (CAR) T-cell therapy, showed efficacy in patients with refractory …

Outcomes in refractory diffuse large B-cell lymphoma: results from the international SCHOLAR-1 study

M Crump, SS Neelapu, U Farooq… - Blood, The Journal …, 2017 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin
lymphoma. Although 5-year survival rates in the first-line setting range from 60% to 70%, up …

Phase 2 study of the bispecific T-cell engager (BiTE) antibody blinatumomab in relapsed/refractory diffuse large B-cell lymphoma

A Viardot, ME Goebeler, G Hess… - Blood, The Journal …, 2016 - ashpublications.org
Few patients with relapsed/refractory diffuse large B-cell lymphoma (DLBCL) achieve
prolonged disease-free survival. Blinatumomab, a bispecific T-cell engaging antibody …

Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte …

JF DiPersio, IN Micallef, PJ Stiff, BJ Bolwell… - Journal of Clinical …, 2009 - ascopubs.org
Purpose This study evaluates the safety and efficacy of plerixafor (AMD3100), a CXCR4
antagonist, in mobilizing hematopoietic stem cells for autologous stem-cell transplantation in …

Normalization of pre-ASCT, FDG-PET imaging with second-line, non–cross-resistant, chemotherapy programs improves event-free survival in patients with Hodgkin …

CH Moskowitz, MJ Matasar, AD Zelenetz… - Blood, The Journal …, 2012 - ashpublications.org
We previously reported that remission duration< 1 year, extranodal disease, and B
symptoms before salvage chemotherapy (SLT) can stratify relapsed or refractory Hodgkin …

A 2-step comprehensive high-dose chemoradiotherapy second-line program for relapsed and refractory Hodgkin disease: analysis by intent to treat and development …

CH Moskowitz, SD Nimer, AD Zelenetz… - Blood, The Journal …, 2001 - ashpublications.org
Salvage of patients with relapsed and refractory Hodgkin disease (HD) with high-dose
chemoradiotherapy (HDT) and autologous stem cell transplantation (ASCT) results in event …

Risk-adapted dose-dense immunochemotherapy determined by interim FDG-PET in advanced-stage diffuse large B-cell lymphoma

CH Moskowitz, H Schöder… - Journal of clinical …, 2010 - ascopubs.org
Purpose In studies of diffuse large B-cell lymphoma, positron emission tomography with
[18F] fluorodeoxyglucose (FDG-PET) performed after two to four cycles of chemotherapy has …

Rituximab and ICE as second-line therapy before autologous stem cell transplantation for relapsed or primary refractory diffuse large B-cell lymphoma

T Kewalramani, AD Zelenetz, SD Nimer, C Portlock… - Blood, 2004 - ashpublications.org
Patients with relapsed or primary refractory diffuse large B-cell lymphoma (DLBCL) who
achieve complete response (CR) before autologous stem cell transplantation (ASCT) …