The relationship between high-density lipoproteins (HDLs), HDL-cholesterol (HDLsingle
bond C) and cancer incidence and mortality is controversial. Although most studies …

Extensive research has been carried out to understand and elucidate the mechanisms of
paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular …

We studied the potential mechanisms of valproic acid (VPA) in the treatment of glioblastoma
multiforme (GBM). Using the human U87, GBM8401, and DBTRG-05MG GBM-derived cell …

In the present scenario of increased accumulation of pesticides in the environment, it is
important to understand its impact on human health. The focus is on gene–environment …

Ovarian cancer (OC) is most lethal malignancy among all gynecological cancer. Large
bodies of evidences suggest that mitochondrial-derived ROS play a critical role in the …

Increases in the generation of reactive oxygen species and decreases in antioxidant
enzyme activities with aging have been reported in the prostate, and are also observed in …

Q192R and L55M polymorphism were considered to be associated with the development of
multiple cancers. Nevertheless, the results of these researches were inconclusive and …

Paraoxonase is an HDL-associated enzyme that plays a preventive role against oxidative
stress, which is thought to contribute to cancer development. PON1 activity varies widely …

The drastic increase in pesticide applications makes human exposure inevitable either
through environment or occupation. Pesticide toxicity causes many adverse health effects …

Common genetic variation Q192R in the paraoxonase 1 (PON1) gene has been considered
to be implicated in the development of many cancers. Nevertheless, results from the related …