Advances in sensor developments for cell culture monitoring

KR Kim, WH Yeo - BMEMat, 2023 - Wiley Online Library
Cell culture encompasses procedures for extracting cells from their natural tissue and
cultivating them under controlled artificial conditions. During this process, various factors …

The machine learning life cycle in chemical operations–status and open challenges

M Gärtler, V Khaydarov, B Klöpper… - Chemie Ingenieur …, 2021 - Wiley Online Library
Artificial intelligence (AI) has received a lot of attention with many publications in recent
years. Interestingly related projects in the industry are mostly still in their early stages. We …

Cellular interaction of bone marrow mesenchymal stem cells with polymer and hydrogel 3D microscaffold templates

BNL Costa, RMR Adão, C Maibohm… - … applied materials & …, 2022 - ACS Publications
Biomimicking biological niches of healthy tissues or tumors can be achieved by means of
artificial microenvironments, where structural and mechanical properties are crucial …

Transformative materials to create 3D functional human tissue models in vitro in a reproducible manner

JL Gerardo‐Nava, J Jansen, D Günther… - Advanced …, 2023 - Wiley Online Library
Recreating human tissues and organs in the petri dish to establish models as tools in
biomedical sciences has gained momentum. These models can provide insight into …

Engineering Vascular Bioreactor Systems to Closely Mimic Physiological Forces In Vitro

TC Mitchell, NL Feng, YT Lam, PL Michael… - … Engineering Part B …, 2023 - liebertpub.com
In vitro models of the vasculature play an important role in biomedical discovery research,
with diverse applications in vascular biology, drug discovery, and tissue engineering. These …

[HTML][HTML] Assessing the mass transfer coefficient in jet bioreactors with classical computer vision methods and neural networks algorithms

I Nizovtseva, V Palmin, I Simkin, I Starodumov… - Algorithms, 2023 - mdpi.com
Development of energy-efficient and high-performance bioreactors requires progress in
methods for assessing the key parameters of the biosynthesis process. With a wide variety of …

[HTML][HTML] A high-resolution real-time quantification of astrocyte cytokine secretion under shear stress for investigating hydrocephalus shunt failure

F Khodadadei, AP Liu, CA Harris - Communications biology, 2021 - nature.com
It has been hypothesized that physiological shear forces acting on medical devices
implanted in the brain significantly accelerate the rate to device failure in patients with …

Keeping it organized: multicompartment constructs to mimic tissue heterogeneity

A Sanchez‐Rubio, V Jayawarna… - Advanced …, 2023 - Wiley Online Library
Tissue engineering aims at replicating tissues and organs to develop applications in vivo
and in vitro. In vivo, by engineering artificial constructs using functional materials and cells to …

[HTML][HTML] Small-Scale Fluidized Bed Bioreactor for Long-Term Dynamic Culture of 3D Cell Constructs and in vitro Testing

J Mendonça da Silva, E Erro, M Awan… - … in Bioengineering and …, 2020 - frontiersin.org
With the increasing interest in three-dimensional (3D) cell constructs that better represent
native tissues, comes the need to also invest in devices, ie, bioreactors, that provide a …

[HTML][HTML] Online measurement system for dynamic flow bioreactors to study barrier integrity of hiPSC-based blood–brain barrier in vitro models

J Choi, S Mathew, S Oerter, A Appelt-Menzel… - Bioengineering, 2022 - mdpi.com
Electrochemical impedance spectroscopy (EIS) is a noninvasive, reliable, and efficient
method to analyze the barrier integrity of in vitro tissue models. This well-established tool is …