Therapeutically harnessing extracellular vesicles
The field of extracellular vesicle (EV) research has developed rapidly over the last decade
from the study of fundamental biology to a subject of significant clinical relevance. The …
from the study of fundamental biology to a subject of significant clinical relevance. The …
Plant‐derived extracellular vesicles: Recent advancements and current challenges on their use for biomedical applications
MQ Lian, WH Chng, J Liang, HQ Yeo… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) represent a diverse class of lipid bilayer membrane vesicles
released by both animal and plant cells. These ubiquitous vesicles are involved in …
released by both animal and plant cells. These ubiquitous vesicles are involved in …
Engineered neutrophil-derived exosome-like vesicles for targeted cancer therapy
Neutrophils are the most abundant innate immune cells in human circulation; however, their
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
derived exosomes have been rarely studied for tumor treatment. Here, we reported that …
Opportunities and challenges for co-delivery nanomedicines based on combination of phytochemicals with chemotherapeutic drugs in cancer treatment
Q Gao, J Feng, W Liu, C Wen, Y Wu, Q Liao… - Advanced drug delivery …, 2022 - Elsevier
The therapeutic limitations such as insufficient efficacy, drug resistance, metastasis, and
undesirable side effects are frequently caused by the long duration monotherapy based on …
undesirable side effects are frequently caused by the long duration monotherapy based on …
Engineering macrophages for cancer immunotherapy and drug delivery
Macrophages play an important role in cancer development and metastasis.
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2 …
RNA delivery by extracellular vesicles in mammalian cells and its applications
The term 'extracellular vesicles' refers to a heterogeneous population of vesicular bodies of
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
cellular origin that derive either from the endosomal compartment (exosomes) or as a result …
Therapeutic roles of mesenchymal stem cell-derived extracellular vesicles in cancer
Z Weng, B Zhang, C Wu, F Yu, B Han, B Li… - Journal of hematology & …, 2021 - Springer
Extracellular vesicles (EVs) are cell-derived membrane structures enclosing proteins, lipids,
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
RNAs, metabolites, growth factors, and cytokines. EVs have emerged as essential …
Exosome-based smart drug delivery tool for cancer theranostics
R Kar, R Dhar, S Mukherjee, S Nag… - ACS biomaterials …, 2023 - ACS Publications
Exosomes are the phospholipid-membrane-bound subpopulation of extracellular vesicles
derived from the plasma membrane. The main activity of exosomes is cellular …
derived from the plasma membrane. The main activity of exosomes is cellular …
Isolation and characterization of extracellular vesicle subpopulations from tissues
R Crescitelli, C Lässer, J Lötvall - Nature protocols, 2021 - nature.com
Extracellular vesicles (EVs) are lipid bilayered membrane structures released by all cells.
Most EV studies have been performed by using cell lines or body fluids, but the number of …
Most EV studies have been performed by using cell lines or body fluids, but the number of …
Liposomes and extracellular vesicles as drug delivery systems: A comparison of composition, pharmacokinetics, and functionalization
L van der Koog, TB Gandek… - Advanced healthcare …, 2022 - Wiley Online Library
Over the past decades, lipid‐based nanoparticle drug delivery systems (DDS) have caught
the attention of researchers worldwide, encouraging the field to rapidly develop improved …
the attention of researchers worldwide, encouraging the field to rapidly develop improved …