Phytocannabinoids: origins and biosynthesis
T Gülck, BL Møller - Trends in plant science, 2020 - cell.com
Phytocannabinoids are bioactive natural products found in some flowering plants, liverworts,
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …
and fungi that can be beneficial for the treatment of human ailments such as pain, anxiety …
Acute and chronic effects of cannabinoids on human cognition—a systematic review
SJ Broyd, HH Van Hell, C Beale, M Yuecel… - Biological psychiatry, 2016 - Elsevier
Cannabis use has been associated with impaired cognition during acute intoxication as well
as in the unintoxicated state in long-term users. However, the evidence has been mixed and …
as in the unintoxicated state in long-term users. However, the evidence has been mixed and …
Cortical structural differences in major depressive disorder correlate with cell type-specific transcriptional signatures
Major depressive disorder (MDD) has been shown to be associated with structural
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
abnormalities in a variety of spatially diverse brain regions. However, the correlation …
Adverse health effects of marijuana use
ND Volkow, RD Baler, WM Compton… - New England Journal …, 2014 - Mass Medical Soc
As marijuana use becomes legal in some states, the dominant public opinion is that
marijuana is a harmless source of mood alteration. Although the harms associated with …
marijuana is a harmless source of mood alteration. Although the harms associated with …
From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology
A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
Neurobiological interactions between stress and the endocannabinoid system
Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …
many neurobehavioral processes. A growing body of work indicates that the …
High-resolution crystal structure of the human CB1 cannabinoid receptor
The human cannabinoid G-protein-coupled receptors (GPCRs) CB1 and CB2 mediate the
functional responses to the endocannabinoids anandamide and 2-arachidonyl glycerol (2 …
functional responses to the endocannabinoids anandamide and 2-arachidonyl glycerol (2 …
Synthetic cannabinoids: epidemiology, pharmacodynamics, and clinical implications
MS Castaneto, DA Gorelick, NA Desrosiers… - Drug and alcohol …, 2014 - Elsevier
Background Synthetic cannabinoids (SC) are a heterogeneous group of compounds
developed to probe the endogenous cannabinoid system or as potential therapeutics …
developed to probe the endogenous cannabinoid system or as potential therapeutics …
The endocannabinoid system in guarding against fear, anxiety and stress
The endocannabinoid (eCB) system has emerged as a central integrator linking the
perception of external and internal stimuli to distinct neurophysiological and behavioural …
perception of external and internal stimuli to distinct neurophysiological and behavioural …
[HTML][HTML] Cannabinoids in the treatment of epilepsy: hard evidence at last?
E Perucca - Journal of epilepsy research, 2017 - ncbi.nlm.nih.gov
The interest in cannabis-based products for the treatment of refractory epilepsy has
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …
skyrocketed in recent years. Marijuana and other cannabis products with high content in Δ …